Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
MEISTER PAUL M
   2. Issuer Name and Ticker or Trading Symbol
THERMO FISHER SCIENTIFIC INC. [TMO] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
81 WYMAN STREET, P.O. BOX 9046		 3. Date of Earliest Transaction (Month/Day/Year)
01/03/2007
(Street)

WALTHAM, MA 024549046		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 01/03/2007   F   190,050 D $ 45.17 702,950 (1) D  
Common Stock 01/03/2007   M   200,000 A $ 19.62 902,950 D  
Common Stock 01/03/2007   S(2)   200,000 D $ 45.29 (3) 702,950 D  
Common Stock 01/04/2007   M   177,512 A $ 19.62 880,462 D  
Common Stock 01/04/2007   S(2)   255,462 D $ 45.5 (4) 625,000 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $ 19.62 01/03/2007   M     200,000 11/09/2006 09/26/2008 Common Stock 200,000 $ 0 177,512 D  
Stock Option (Right to Buy) $ 19.62 01/04/2007   M     177,512 11/09/2006 09/26/2008 Common Stock 177,512 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
MEISTER PAUL M
81 WYMAN STREET
P.O. BOX 9046
WALTHAM, MA 024549046		   X      

Signatures

 By: Barbara J. Lucas, Attorney-in-Fact for Paul M. Meister   01/05/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes 352,950 shares previously held indirectly through a trust for the benefit of the reporting person, and that were distributed to the reporting person effective as of January 3, 2007, and are now owned directly.
(2) The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 13, 2006.
(3) The sales price shown is the average sales price for all shares sold on January 3, 2007, actual denominations are as follows: 50,000 shares at $45.05; 100,000 shares at $45.25; 23,400 shares at $45.52; 25,000 shares at $45.70 and 1,600 shares at $45.75.
(4) The sales price shown is the average sales price for all shares sold on January 4, 2007, actual denominations are as follows: 53,800 shares at $45.30; 4,500 shares at $45.31; 100 shares at $45.33; 1,600 shares at $45.35; 2,400 shares at $45.36; 2,300 shares at $45.37; 2,000 shares at $45.38; 1,300 shares at $45.39; 2,000 shares at $45.40; 2,500 shares at $45.41; 800 shares at $45.42; 1,500 shares at $45.45; 200 shares at $45.46; 73,547 shares at $45.50; 9,300 shares at $45.51; 7,000 shares at $45.52; 3,700 shares at $45.53; 3,800 shares at $45.54; 2,700 shares at $45.55; 400 shares at $45.56; 5,715 shares at $45.57; 700 shares at $45.58; 2,202 shares at $45.62; 12,798 shares at $45.63; 12,600 shares at $45.65; 4,700 shares at $45.66; 2,200 shares at $45.67; 35,400 shares at $45.68; 2,900 shares at $45.69; 300 shares at $45.70 and 500 shares at $45.71.

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