SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                 SCHEDULE 13G/A
                                 (Rule 13d-102)

           INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO
            RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED
                            PURSUANT TO RULE 13d-2(b)
                                (Amendment No. 3)


                         REGENERON PHARMACEUTICALS, INC
  ----------------------------------------------------------------------------
                                (Name of Issuer)


                         Common Stock, $0.001 par value
  ----------------------------------------------------------------------------
                         (Title of Class of Securities)


                                   75886F 10 7
  ----------------------------------------------------------------------------
                                 (CUSIP Number)


                                December 31, 2003
  ----------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

                o          Rule 13d-1(b)

                x          Rule 13d-1(c)

                o          Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

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CUSIP No. 75886F 10 7                                             13G/A
   1    NAME OF REPORTING PERSONS
        I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

        Leonard S. Schleifer, M.D., Ph.D.
   2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                (a)   o
                                                                         (b)   o
   3    SEC USE ONLY
   4    CITIZENSHIP OR PLACE OF ORGANIZATION

        United States of America
             NUMBER OF               5             SOLE VOTING POWER
               SHARES
            BENEFICIALLY                            2,616,950
              OWNED BY
                EACH
             REPORTING
            PERSON WITH
                                     6             SHARED VOTING POWER

                                                   0
                                     7             SOLE DISPOSITIVE POWER

                                                   2,616,950

                                     8             SHARED DISPOSITIVE POWER
                                                   0

   9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

        2,616,950
   10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
        SHARES*                                                          [X]

   11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

        4.7%
   12   TYPE OF REPORTING PERSON*

        IN

        *SEE INSTRUCTIONS BEFORE FILLING OUT


                                 SCHEDULE 13G/A
                                 --------------

CUSIP No. 75886F 10 7

Item 1.  (a)      Name of Issuer

                  Regeneron Pharmaceuticals, Inc.


Item 1.  (b)      Address of Issuer's Principal Executive Offices

                  777 Old Saw Mill River Road
                  Tarrytown, New York 10591

Item 2.  (a)      Name of Person Filing

                  Leonard S. Schleifer, M.D., Ph.D.

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Item 2.  (b)      Address of Principal Business Office or, if none, residence

                  777 Old Saw Mill River Road
                  Tarrytown, New York 10591

Item 2.  (c)      Citizenship

                  United States of America

Item 2.  (d)      Title of Class of Securities

                  Common Stock, par value $.001 per share

Item 2.  (e)      CUSIP Number

                  75886F 10 7

Item 3.           Not Applicable.

Item 4.           Ownership

         (a)      Amount Beneficially Owned

                           Regeneron Pharmaceuticals, Inc. (the "Issuer") has
                  two classes of outstanding capital stock, Common Stock, par
                  value $.001 per share (the "Common Stock"), holders of which
                  are entitled to one vote per share, and Class A Stock, par
                  value $.001 per share ("Class A Stock"), holders of which are
                  entitled to ten votes per share. The Class A Stock is not
                  registered pursuant to Section 12 of the Securities Exchange
                  Act of 1934. Each share of Class A Stock may be converted at
                  the option of the holder at any time into one fully paid and
                  non-assessable share of Common Stock. In addition, pursuant to
                  the terms of the Issuer's Certificate of Incorporation, each
                  share of Class A Stock will be automatically converted into
                  one fully paid and non-assessable share of Common Stock upon
                  the transfer of Class A Stock whether by sale, exchange, gift,
                  operation of law, pledge, or otherwise, or upon any transfer
                  of the power to vote such shares by proxy, to a person who is
                  not a "Permitted Transferee" (as such term is defined in the
                  Issuer's Certificate of Incorporation).

                           The Reporting Person is the beneficial owner of
                  1,710,790 shares of Class A Stock and 111,290 shares of Common
                  Stock. In addition, the Reporting Person is the beneficial
                  owner of 794,870 stock options which have vested (or will vest
                  in the next sixty days) and were granted under the Issuer's
                  Long-Term Incentive Plans. Each Stock Option entitles the
                  Reporting Person to purchase one share of Common Stock at an
                  exercise price determined in accordance with the Issuer's
                  Long-Term Incentive Plans.

                           Harriet Schleifer, the wife of the Reporting Person,
                  is the record owner, as custodian for their children, Adam and
                  David Schleifer, of 58,550 shares of Class A Stock and 1,800
                  shares of Common Stock. The Reporting Person disclaims
                  beneficial ownership of such shares.

         (b)      Percent of Class

                           4.7%


         (c)      Number of Shares as to which person has

                  (i)      Sole power to vote or to direct the vote             2,616,950
                                                                       
                  (ii)     Shared power to vote or to direct the vote           0
                  (iii)    Sole power to dispose or to direct the disposition   2,616,950
                  (iv)     Shared power to dispose or to direct the disposition 0






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Item 5.           Ownership of Five Percent or Less of a Class

                  If this statement is being filed to report the fact that as of
                  the date hereof the reporting person has ceased to be the
                  beneficial owner of more than five percent of the class of
                  securities, check the following

                                    [ X ].

Item 6.           Ownership of More than Five Percent on Behalf of Another
                  Person.

                  Not Applicable

Item 7.           Identification and Classification of the Subsidiary Which
                  Acquired the Security Being Reported on by the Parent
                  Holding Company.

                  Not Applicable.

Item 8.           Identification and Classification of Members of the Group.

                  Not Applicable.

Item 9.           Notice and Dissolution of Group.

                  Not Applicable.

Item 10.          Certification.

                  By signing below I certify that, to the best of my knowledge
                  and belief, the securities referred to above were not acquired
                  and are not held for the purpose of or with the effect of
                  changing or influencing the control of the issuer of the
                  securities and were not acquired and are not held in
                  connection with or as a participant in any transaction having
                  that purpose or effect.

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                                   SIGNATURE
                                   ---------

         After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

         Date:    February 18, 2004


        By:
                     /s/ Leonard Schleifer
                     ----------------------
                     Leonard S. Schleifer, M.D., Ph.D.



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                                  End of Filing