Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Thomson Andrew J
 2. Date of Event Requiring Statement (Month/Day/Year)
02/28/2012		 3. Issuer Name and Ticker or Trading Symbol
THERMO FISHER SCIENTIFIC INC. [TMO]
(Last)
(First)
(Middle)
81 WYMAN STREET		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Senior Vice President
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

WALTHAM, MA 02451		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 7,336
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   (1) 02/06/2016 Common Stock 25,000 $ 40 D  
Stock Option (Right to Buy)   (2) 11/20/2016 Common Stock 12,700 $ 46.56 D  
Stock Option (Right to Buy)   (3) 02/23/2018 Common Stock 16,900 $ 54.97 D  
Stock Option (Right to Buy) 03/05/2011(4) 03/05/2017 Common Stock 8,600 $ 49.49 D  
Stock Option (Right to Buy) 03/05/2012(5) 03/05/2017 Common Stock 3,650 $ 49.49 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Thomson Andrew J
81 WYMAN STREET
WALTHAM, MA 02451		       Senior Vice President  

Signatures

Barbara J. Lucas, Attorney-in-Fact for Andrew J. Thomson 02/29/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The option vested in three equal installments on February 6, 2010, 2011 and 2012.
(2) The option is exercisable in three equal annual installments. The first and second installments became exercisable on November 20, 2010 and 2011, and the third installment will be exercisable on November 20, 2012.
(3) The option is exercisable in four equal annual installments. The first installment became exercisable on February 23, 2012, and the next three installments become exercisable on February 23, 2013, 2014 and 2015.
(4) The option is exercisable in four equal annual installments. The first installment became exercisable on March 5, 2011, and the next three installments become exercisable on March 5, 2012, 2013, and 2014.
(5) The option vests in four equal annual installments beginning on March 5, 2012.
 
Remarks:
Exhibit List      Exhibit 24 - Confirming Statement

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