UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13D
UNDER THE SECURITIES EXCHANGE ACT OF 1934
INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO
RULE 13D-1(a) AND AMENDMENTS THERETO FILED
PURSUANT TO RULE 13D-2(a)
INCYTE GENOMICS, INC.
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(Name of Issuer)
COMMON STOCK, $0.001 PER SHARE
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(Title of Class of Securities)
45337C-10-2
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(CUSIP Number)
BARRY L. BLOOM
655 MADISON AVENUE 8TH FLOOR
NEW YORK, NY 10021
(212) 521-2930
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(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)
AUGUST 5, 2002
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(Date of Event which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following
box. [X]
NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See Rule 13d-7 for other parties
to whom copies are to be sent.
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 (the "Act") or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, see the
Notes).
Page 1 of 20 Pages
SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 2 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
Andrew H. Tisch
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
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6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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7 SOLE VOTING POWER
-0-
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 3,982,135
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH -0-
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
3,982,135
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11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,982,135
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12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
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13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
5.8%
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14 TYPE OF REPORTING PERSON (See Instructions)
IN
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SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 3 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
Daniel R. Tisch
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
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6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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7 SOLE VOTING POWER
52,877
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 3,982,580
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH 52,877
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
3,982,580
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11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
4,035,457
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12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
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13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
5.9%
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14 TYPE OF REPORTING PERSON (See Instructions)
IN
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SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 4 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
James S. Tisch
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
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6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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7 SOLE VOTING POWER
-0-
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 3,982,135
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH -0-
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
3,982,135
--------------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
3,982,135
--------------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
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13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
5.8%
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14 TYPE OF REPORTING PERSON (See Instructions)
IN
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SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 5 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
Thomas J. Tisch
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
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6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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7 SOLE VOTING POWER
-0-
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 4,182,135
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH -0-
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
4,182,135
--------------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
4,182,135
--------------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
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13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
6.1%
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14 TYPE OF REPORTING PERSON (See Instructions)
IN
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SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 6 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
Bonnie J. Tisch
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
--------------------------------------------------------------------------------
3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
--------------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
--------------------------------------------------------------------------------
7 SOLE VOTING POWER
-0-
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 444
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH -0-
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
444
--------------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
444
--------------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
--------------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
0.1%
--------------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON (See Instructions)
IN
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SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 7 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
Julian C. Baker
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
--------------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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7 SOLE VOTING POWER
27,917
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 1,900,567
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH 27,917
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
1,900,567
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11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,928,484
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12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
--------------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
2.9%
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14 TYPE OF REPORTING PERSON (See Instructions)
IN
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SCHEDULE 13D
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CUSIP NO. 45337C-10-2 PAGE 8 OF 20 PAGES
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1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
Felix J. Baker
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(See Instructions) (a) [_]
(b) [X]
--------------------------------------------------------------------------------
3 SEC USE ONLY
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4 SOURCE OF FUNDS (See Instructions)
PF
--------------------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
PURSUANT TO ITEMS 2(d) OR 2(e) [_]
--------------------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
--------------------------------------------------------------------------------
7 SOLE VOTING POWER
-0-
------------------------------------------------------------
NUMBER OF 8 SHARED VOTING POWER
SHARES
BENEFICIALLY 1,900,567
OWNED BY ------------------------------------------------------------
EACH 9 SOLE DISPOSITIVE POWER
REPORTING
PERSON WITH -0-
------------------------------------------------------------
10 SHARED DISPOSITIVE POWER
1,900,567
--------------------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,900,567
--------------------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
EXCLUDES CERTAIN SHARES (See Instructions) [_]
--------------------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
2.8%
--------------------------------------------------------------------------------
14 TYPE OF REPORTING PERSON (See Instructions)
IN
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ITEM 1. SECURITY AND ISSUER.
This statement on Schedule 13D relates to the common stock, par value
$0.001 per share (the "Common Stock") of Incyte Genomics, Inc., a Delaware
corporation (the "Company"). The principal executive offices of the Company are
located at 3160 Porter Drive, Palo Alto, California 94304.
ITEM 2. IDENTITY AND BACKGROUND.
This statement is being filed by Andrew H. Tisch, Daniel R. Tisch,
James S. Tisch, Thomas J. Tisch, Bonnie J. Tisch, Julian C. Baker and Felix J.
Baker (each, a "Reporting Person"). Each of the Reporting Persons is a United
States citizen.
Set forth below is certain information with respect to each of the
Reporting Persons:
NAME BUSINESS ADDRESS PRESENT PRINCIPAL OCCUPATION
---- ---------------- ----------------------------
Andrew H. Tisch 667 Madison Avenue Member, Management Committee,
New York, NY 10021 Loews Corporation (a public
company primarily engaged in
insurance and tobacco)
Daniel R. Tisch c/o Mentor Partners, L.P. General Partner, Mentor
499 Park Avenue Partners, L.P. (a partnership
New York, NY 10022 engaged in investment
activities)
James S. Tisch 667 Madison Avenue President and Chief Operating
New York, NY 10021 Officer, Loews Corporation (a
public company primarily
engaged in insurance and
tobacco)
Thomas J. Tisch 667 Madison Avenue Managing Partner of FLF
New York, NY 10021 Associates and Manager of Four
Partners (partnerships engaged
in investment activities)
Bonnie J. Tisch c/o Mentor Partners, L.P. Wife of Daniel R. Tisch
499 Park Avenue
New York, NY 10022
Page 9 of 20 Pages
NAME BUSINESS ADDRESS PRESENT PRINCIPAL OCCUPATION
---- ---------------- ----------------------------
Julian C. Baker 655 Madison Avenue Managing Member, Baker Bros.
New York, NY 10021 Capital (GP), LLC, Baker
Biotech Capital (GP), LLC,
Baker Biotech Capital II (GP),
LLC and Baker/Tisch Capital
(GP), LLC (manager of
partnerships engaged in
investment activities)
Felix J. Baker 655 Madison Avenue Managing Member, Baker Bros.
New York, NY 10021 Capital (GP), LLC, Baker
Biotech Capital (GP), LLC,
Baker Biotech Capital II (GP),
LLC and Baker/Tisch Capital
(GP), LLC (manager of
partnerships engaged in
investment activities)
During the last five years, none of the Reporting Persons has been
convicted in any criminal proceeding (excluding traffic violations or similar
misdemeanors), and none of the Reporting Persons has been a party to a civil
proceeding of a judicial or administrative body of competent jurisdiction
resulting in his being subject to a judgment, decree or final order enjoining
future violations of, or prohibiting or mandating activities subject to, federal
or state securities laws, or finding any violations with respect to such loss.
ITEM 3. SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION.
The funds used to purchase the shares of Common Stock reported in the
second table under Item 5 below were provided from the available working capital
of the entity indicated as making the purchase. The aggregate price of each
purchase is included in the second table under Item 5 below.
ITEM 4. PURPOSE OF TRANSACTION.
The Reporting Persons have acquired the shares of Common Stock referred
to in Item 5 solely for investment. Each Reporting Person expects to review his
investment position from time to time and may, depending on market conditions or
other factors, increase or decrease such investment position. Whether a
Reporting Person purchases any additional shares of Common Stock or disposes of
any shares of Common Stock and the amount and timing of any such transactions
will depend upon each Reporting Person's individual continuing assessment of
pertinent factors, including the availability of shares for purchase at
particular price levels, the Company's business and prospects, other business
investment opportunities available to the particular Reporting Person, economic
conditions, market conditions, the attitudes and actions of the Board of
Directors and management of the Company, the availability and nature of
opportunities to dispose of the particular Reporting Person's interest in the
Company and other plans and requirements of the particular Reporting Person.
Page 10 of 20 Pages
Julian C. Baker is a director of the Company, and Felix J. Baker
attends and observes meetings of the Company's board of directors.
At the present time, the Reporting Persons do not have any plans or
proposals with respect to any extraordinary corporate transaction involving the
Company or any sale of its assets or any change in its Board of Directors,
management, capitalization, dividend strategy, charter or by-laws, or any other
change in its business or corporate structure or with respect to the delisting
or deregistration of any of its securities including, without limitation, those
matters described in subparagraphs (a) though (j) of Item 4 of Schedule 13D.
ITEM 5. INTEREST IN SECURITIES OF THE ISSUER.
Because of certain business and family relationships among the
Reporting Persons, they are filing as if they constitute a group solely for
informational purposes. By signing this statement, each Reporting Person agrees
that this Statement is filed on his or her behalf. The filing of this statement
is not an admission by any Reporting Person that such Reporting Person and any
other Reporting Person or Reporting Persons constitute a "group" for purposes of
Section 13(d)(3) of the Securities Exchange Act of 1934, as amended, or Rule
13d-5 thereunder. Each Reporting Person disclaims beneficial ownership of, or
pecuniary interest in, any shares of Common Stock owned by any other Reporting
Person, except to the extent that beneficial ownership or pecuniary interest is
expressly reported herein.
Set forth in the table below is the aggregate number of shares of
Common Stock owned by each of the following, together with the percentage of
outstanding shares of Common Stock that such owner ownership represents.
Page 11 of 20 Pages
AMOUNT AND NATURE OF PERCENT OF CLASS
NAME OF BENEFICIAL OWNER BENEFICIAL OWNERSHIP OUTSTANDING (1)
------------------------------------ ----------------------- -----------------
Four Partners 3,522,353 5.2%
Four-Fourteen Partners, LLC 200,000 0.3%
Damial Foundation 52,877 0.1%
Andrew H. Tisch (2) 459,782 0.7%
Daniel R. Tisch (2) 459,782 0.7%
James S. Tisch (2) 459,782 0.7%
Thomas J. Tisch (2) 459,782 0.7%
Bonnie J. Tisch 444 0.0%
Baker/Tisch Investments, L.P. 278,593 0.4%
Baker Bros. Investments, L.P. 147,964 0.2%
Baker Bros. Investments II, L.P. 66,040 0.1%
Baker Biotech Fund I, L.P. 886,855 1.3%
Baker Biotech Fund II, L.P. 463,457 0.7%
FBB Associates 55,658 0.1%
Julian C. Baker 27,917(3) 0.1%
Total 7,543,286 11.0%
(1) The ownership percentages set forth in the table above are based upon
67,529,022 shares of Common Stock outstanding, as reported on the Company's
Form 10-Q for the fiscal quarter ended June 30, 2002, plus the shares that
each person listed has the right to acquire upon conversion of 5.5%
Convertible Subordinated Notes due 2007 at the presently applicable
conversion price of $67.4195 or exercise of non-qualified stock options.
(2) Includes shares held by the Reporting Person in his individual capacity or
by a trust in which the Reporting Person is the trustee or managing trustee
and has voting or investment control over securities held by such trust.
(3) Represents shares that may be acquired upon exercise of non-qualified stock
options.
Each person listed above has sole power to vote or direct the vote of
and to dispose or direct the disposition of the securities listed after such
person's name, except as follows:
(1) By virtue of their status as managing trustees of the trusts that are the
general partners of Four Partners, a New York general partnership, Andrew
H. Tisch, Daniel R. Tisch, James S. Tisch and Thomas J. Tisch may be deemed
to have shared beneficial ownership of securities owned by Four Partners
and shared power to vote or direct the vote of and to dispose or direct the
disposition of such securities.
Page 12 of 20 Pages
(2) By virtue of his status as manager of Four-Fourteen Partners, LLC, Thomas
J. Tisch may be deemed to be the beneficial owner of securities owned by
Four-Fourteen Partners, LLC and to have power to vote or direct the vote of
and to dispose or direct the disposition of securities owned by
Four-Fourteen Partners, LLC.
(3) Daniel R. Tisch may be deemed to be the beneficial owner of securities
owned by Damial Foundation, a Delaware not-for-profit corporation, and to
have power to vote or direct the vote of and to dispose or direct the
disposition of securities owned by Damial Foundation.
(4) Daniel R. Tisch may be deemed to share the power to vote or direct the vote
of and to dispose or direct the disposition of securities owned by his
wife, Bonnie J. Tisch, as custodian for their son, Michael J. Tisch.
(5) Julian C. Baker and Felix J. Baker, by virtue of their control of entities
that have the power to control the investment decisions of Baker/Tisch
Investments, L.P., Baker Bros. Investments, L.P., Baker Bros. Investments
II, L.P., Baker Biotech Fund I, L.P. and Baker Biotech Fund II, L.P., may
each be deemed to be the beneficial owners of securities owned by such
entities and may be deemed to have shared power to vote or direct the vote
of and to dispose or direct the disposition of such securities. Julian C.
Baker and Felix J. Baker are also the sole partners of FBB Associates, a
general partnership, and as such may be deemed to be beneficial owners of
securities owned by FBB Associates and to have shared power to vote or
direct the vote of and to dispose or direct the disposition of such
securities.
The following purchases of Common Stock were effected by the entities
noted below during the 60 days preceding the date hereof. None of the Reporting
Persons has effected any other transactions in Common Stock during the 60 days
preceding the date hereof. The following transactions were effected through
NASDAQ.
NUMBER OF PRICE/ AGGREGATE
NAME DATE SHARES SHARE AMOUNT
------------------------------- ---------- ----------- --------- ----------
Four Partners 07/10/02 14,000 $5.37 $75,506
Four Partners 07/11/02 48,333 $5.60 $271,453
Four Partners 07/16/02 5,100 $6.23 $31,898
Four Partners 07/18/02 20,000 $6.14 $123,230
Four Partners 07/24/02 12,450 $5.65 $70,601
Four Partners 07/24/02 26,600 $5.93 $158,395
Four Partners 07/29/02 16,000 $5.90 $94,707
Four Partners 07/30/02 36,600 $5.88 $216,064
Page 13 of 20 Pages
NUMBER OF PRICE/ AGGREGATE
NAME DATE SHARES SHARE AMOUNT
------------------------------- ---------- ----------- --------- ----------
Four Partners 07/31/02 22,200 $6.00 $133,633
Four Partners 08/01/02 56,700 $5.94 $338,108
Four Partners 08/02/02 19,450 $5.82 $113,569
Four Partners 08/05/02 37,000 $5.86 $217,623
Four Partners 08/06/02 23,300 $6.00 $140,247
Four Partners 08/07/02 115,900 $5.96 $693,488
Baker Biotech Fund I, L.P. 07/10/02 12,320 $5.37 $66,446
Baker Biotech Fund I, L.P. 07/11/02 42,530 $5.60 $238,861
Baker Biotech Fund I, L.P. 07/16/02 4,500 $6.23 $28,145
Baker Biotech Fund I, L.P. 07/18/02 17,550 $6.14 $108,134
Baker Biotech Fund I, L.P. 07/24/02 10,950 $5.65 $62,095
Baker Biotech Fund I, L.P. 07/24/02 23,400 $5.93 $139,340
Baker Biotech Fund I, L.P. 07/29/02 13,800 $5.90 $81,685
Baker Biotech Fund I, L.P. 07/30/02 32,200 $5.88 $190,089
Baker Biotech Fund I, L.P. 07/31/02 19,400 $6.00 $116,778
Baker Biotech Fund I, L.P. 08/01/02 49,000 $5.94 $292,192
Baker Biotech Fund I, L.P. 08/02/02 16,800 $5.82 $98,095
Baker Biotech Fund I, L.P. 08/05/02 32,100 $5.86 $188,803
Baker Biotech Fund I, L.P. 08/06/02 20,150 $6.00 $121,287
Baker Biotech Fund I, L.P. 08/07/02 100,100 $5.96 $598,948
Baker Biotech Fund I, L.P. 08/08/02 96,000 $5.99 $577,286
Baker Biotech Fund I, L.P. 08/09/02 300 $5.75 $1,731
Baker Biotech Fund II, L.P. 07/10/02 11,480 $5.37 $61,915
Baker Biotech Fund II, L.P. 07/11/02 39,630 $5.60 $222,574
Baker Biotech Fund II, L.P. 07/16/02 4,150 $6.23 $25,956
Baker Biotech Fund II, L.P. 07/18/02 16,250 $6.14 $100,124
Page 14 of 20 Pages
NUMBER OF PRICE/ AGGREGATE
NAME DATE SHARES SHARE AMOUNT
------------------------------- ---------- ----------- --------- ----------
Baker Biotech Fund II, L.P. 07/24/02 10,150 $5.65 $57,559
Baker Biotech Fund II, L.P. 07/24/02 21,700 $5.93 $129,217
Baker Biotech Fund II, L.P. 07/29/02 12,800 $5.90 $75,766
Baker Biotech Fund II, L.P. 07/30/02 29,850 $5.88 $176,216
Baker Biotech Fund II, L.P. 07/31/02 18,000 $6.00 $108,351
Baker Biotech Fund II, L.P. 08/01/02 46,747 $5.94 $278,757
Baker Biotech Fund II, L.P. 08/02/02 16,050 $5.82 $93,716
Baker Biotech Fund II, L.P. 08/05/02 30,600 $5.86 $179,980
Baker Biotech Fund II, L.P. 08/06/02 19,200 $6.00 $115,569
Baker Biotech Fund II, L.P. 08/07/02 95,500 $5.96 $571,424
Baker Biotech Fund II, L.P. 08/08/02 91,600 $5.99 $550,827
Baker Biotech Fund II, L.P. 08/09/02 250 $5.75 $1,443
Baker Bros. Investments, L.P. 07/10/02 1,120 $5.37 $6,041
Baker Bros. Investments, L.P. 07/11/02 3,870 $5.60 $21,735
Baker Bros. Investments, L.P. 07/16/02 450 $6.23 $2,815
Baker Bros. Investments, L.P. 07/18/02 1,750 $6.14 $10,783
Baker Bros. Investments, L.P. 07/24/02 1,100 $5.65 $6,238
Baker Bros. Investments, L.P. 07/24/02 2,300 $5.93 $13,696
Baker Bros. Investments, L.P. 07/29/02 1,400 $5.90 $8,287
Baker Bros. Investments, L.P. 07/30/02 3,200 $5.88 $18,891
Baker Bros. Investments, L.P. 07/31/02 1,950 $6.00 $11,738
Baker Bros. Investments, L.P. 08/01/02 5,000 $5.94 $29,816
Baker Bros. Investments, L.P. 08/02/02 1,700 $5.82 $9,926
Baker Bros. Investments, L.P. 08/05/02 3,300 $5.86 $19,410
Baker Bros. Investments, L.P. 08/06/02 2,050 $6.00 $12,339
Baker Bros. Investments, L.P. 08/07/02 10,150 $5.96 $60,733
Page 15 of 20 Pages
NUMBER OF PRICE/ AGGREGATE
NAME DATE SHARES SHARE AMOUNT
------------------------------- ---------- ----------- --------- ----------
Baker Bros. Investments, L.P. 08/08/02 9,700 $5.99 $58,330
Baker Bros. Investments II, L.P. 07/10/02 1,120 $5.37 $6,041
Baker Bros. Investments II, L.P. 07/11/02 3,870 $5.60 $21,735
Baker Bros. Investments II, L.P. 07/16/02 450 $6.23 $2,815
Baker Bros. Investments II, L.P. 07/18/02 1,800 $6.14 $11,091
Baker Bros. Investments II, L.P. 07/24/02 1,100 $5.65 $6,238
Baker Bros. Investments II, L.P. 07/24/02 2,400 $5.93 $14,291
Baker Bros. Investments II, L.P. 07/29/02 1,400 $5.90 $8,287
Baker Bros. Investments II, L.P. 07/30/02 3,250 $5.88 $19,186
Baker Bros. Investments II, L.P. 07/31/02 1,950 $6.00 $11,738
Baker Bros. Investments II, L.P. 08/01/02 5,100 $5.94 $30,412
Baker Bros. Investments II, L.P. 08/02/02 1,750 $5.82 $10,218
Baker Bros. Investments II, L.P. 08/05/02 3,300 $5.86 $19,410
Baker Bros. Investments II, L.P. 08/06/02 2,100 $6.00 $12,640
Baker Bros. Investments II, L.P. 08/07/02 10,450 $5.96 $62,528
Baker Bros. Investments II, L.P. 08/08/02 10,000 $5.99 $60,134
Baker/Tisch Investments, L.P. 07/10/02 1,960 $5.37 $10,571
Baker/Tisch Investments, L.P. 07/11/02 6,767 $5.60 $38,006
Baker/Tisch Investments, L.P. 07/16/02 650 $6.23 $4,065
Baker/Tisch Investments, L.P. 07/18/02 2,650 $6.14 $16,328
Baker/Tisch Investments, L.P. 07/24/02 1,650 $5.65 $9,357
Baker/Tisch Investments, L.P. 07/24/02 3,500 $5.93 $20,842
Baker/Tisch Investments, L.P. 07/29/02 2,100 $5.90 $12,430
Baker/Tisch Investments, L.P. 07/30/02 4,900 $5.88 $28,927
Baker/Tisch Investments, L.P. 07/31/02 3,000 $6.00 $18,059
Baker/Tisch Investments, L.P. 08/01/02 7,600 $5.94 $45,320
Page 16 of 20 Pages
NUMBER OF PRICE/ AGGREGATE
NAME DATE SHARES SHARE AMOUNT
------------------------------- ---------- ----------- --------- ----------
Baker/Tisch Investments, L.P. 08/02/02 2,600 $5.82 $15,181
Baker/Tisch Investments, L.P. 08/05/02 4,973 $5.86 $29,250
Baker/Tisch Investments, L.P. 08/06/02 3,123 $6.00 $18,798
Baker/Tisch Investments, L.P. 08/07/02 15,500 $5.96 $92,744
Baker/Tisch Investments, L.P. 08/08/02 14,900 $5.99 $89,600
Baker/Tisch Investments, L.P. 08/09/02 50 $5.75 $289
Page 17 of 20 Pages
ITEM 6. CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH RESPECT
TO SECURITIES OF THE ISSUER.
None of the Reporting Persons has any contracts, arrangements or
understandings with any other Reporting Person or with any other person with
respect to the securities of the Company.
ITEM 7. MATERIAL TO BE FILED AS EXHIBITS.
Exhibit 1. Agreement regarding the joint filing of this statement.
Page 18 of 20 Pages
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
August 15, 2002
By: /s/ Andrew H. Tisch
-------------------------------------
Andrew H. Tisch
By: /s/ Daniel R. Tisch
-------------------------------------
Daniel R. Tisch
By: /s/ James S. Tisch
-------------------------------------
James S. Tisch
By: /s/ Thomas J. Tisch
-------------------------------------
Thomas J. Tisch
By: /s/ Bonnie J. Tisch
-------------------------------------
Bonnie J. Tisch
By: /s/ Julian C. Baker
-------------------------------------
Julian C. Baker
By: /s/ Felix J. Baker
-------------------------------------
Felix J. Baker
Page 19 of 20 Pages