UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                   FORM 13F

                             FORM 13F COVER PAGE

Report for the Calendar Year or Quarter Ended: June 30, 2010

Check here if Amendment [ ]; Amendment Number:
This Amendment (Check only one.): [ ] is a restatement.
                                  [ ] adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:GENERAL AMERICAN INVESTORS COMPANY, INC.
Address: 100 PARK AVE 35TH FLOOR
         NEW YORK, NY 10017

13F File Number: 28-461

The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.



Person Signing this Report on Behalf of Reporting Manager:

Name: Eugene S. Stark
Title: Vice-President, Administration
Phone: 212-916-8447
Signature, Place, and Date of Signing:

  Eugene S. Stark   New York, NY   August 03, 2010


Report Type (Check only one.):

[X]    13F HOLDINGS REPORT.

[ ]    13F NOTICE.

[ ]    13F COMBINATION REPORT.


List of Other Managers Reporting for this Manager:

        Form 13F File Number                Name


I AM SIGNING THIS REPORT AS REQUIRED BY THE SECURITIES EXCHANGE ACT OF 1934.


FORM 13F SUMMARY PAGE


Report Summary:

Number of Other Included Managers:       0

Form 13F Information Table Entry Total:  60

Form 13F Information Table Value Total:  $836356357



List of Other Included Managers:

No.   13F File Number    Name





                                                             VALUE    SHARES/ SH/ PUT/ INVSTMT            -----VOTING AUTHORITY-----
  NAME OF ISSUER                 -TITLE OF CLASS- --CUSIP-- x$1000    PRN AMT PRN CALL DSCRETN -MANAGERS-     SOLE   SHARED     NONE
    COLUMN 1                     COLUMN 2         COLUMN 3     COLUMN 4       COLUMN 5    COLUMN 6   COLUMN 7            COLUMN 8
-----------------                ----------       ----------   ----------     ----------  ---------- ---------          ----------
                                                                                                  
Apple Inc.                       COMMON           037833100    15092    60000 SH       SOLE                  60000        0    0
ABB Ltd. ADR                     COMMON           000375204    20736  1200000 SH       SOLE                1200000        0    0
Arch Capital Group Ltd.          COMMON           G0450A105    23468   315000 SH       SOLE                 315000        0    0
Adams Express Company            COMMON           006212104     1163   128815 SH       SOLE                 128815        0    0
Alexander & Baldwin, Inc.        COMMON           014482103     7031   236100 SH       SOLE                 236100        0    0
Amgen Inc.                       COMMON           031162100     2104    40000 SH       SOLE                  40000        0    0
Alpha Natural Resources, Inc.    COMMON           02076X102     8948   264200 SH       SOLE                 264200        0    0
Apache Corporation               COMMON           037411105    24876   295478 SH       SOLE                 295478        0    0
ASML Holding N.V.                COMMON           N07059186    19229   700000 SH       SOLE                 700000        0    0
American Express Company         COMMON           025816109    12903   325000 SH       SOLE                 325000        0    0
Berkshire Hathaway Inc. Class A  COMMON           084670108    13200      110 SH       SOLE                    110        0    0
Celgene Corporation              COMMON           151020104     3049    60000 SH       SOLE                  60000        0    0
Cephalon, Inc.                   COMMON           156708109    21684   382100 SH       SOLE                 382100        0    0
Central Securities Corporation   COMMON           155123102      652    35500 SH       SOLE                  35500        0    0
Canadian Natural Resources       COMMON           136385101     8308   250000 SH       SOLE                 250000        0    0
Costco Wholesale Corporation     COMMON           22160K105    31527   575000 SH       SOLE                 575000        0    0
Cisco Systems, Inc.              COMMON           17275R102    20458   960000 SH       SOLE                 960000        0    0
CEMEX, S.A. de C.V. ADR          COMMON           151290889    18826  1946880 SH       SOLE                1946880        0    0
Cytokinetics, Incorporated       COMMON           23282W100     1256   529900 SH       SOLE                 529900        0    0
Dell Inc.                        COMMON           24702R101    15557  1290000 SH       SOLE                1290000        0    0
Diageo plc ADR                   COMMON           25243Q205    21959   350000 SH       SOLE                 350000        0    0
Devon Energy Corporation         COMMON           25179M103     7923   130062 SH       SOLE                 130062        0    0
Epoch Holding Corporation        COMMON           29428R103    20450  1666667 SH       SOLE                1666667        0    0
Fidelity National Financial, Inc COMMON           31620R105     9743   750000 SH       SOLE                 750000        0    0
Gilead Sciences, Inc.            COMMON           375558103    18665   544500 SH       SOLE                 544500        0    0
Halliburton Company              COMMON           406216101    19640   800000 SH       SOLE                 800000        0    0
Hewitt Associates, Inc.Class A   COMMON           42822Q100    16062   466100 SH       SOLE                 466100        0    0
International Game Technology    COMMON           459902102    11775   750000 SH       SOLE                 750000        0    0
J.C. Penney Company, Inc.        COMMON           708160106     8592   400000 SH       SOLE                 400000        0    0
JPMorgan Chase & Co.             COMMON           46625H100    13729   375000 SH       SOLE                 375000        0    0
JPMorgan Chase & Co.             COMMON           46634E114     1959   155000 SH       SOLE                 155000        0    0
Leap Wireless International, Inc COMMON           521863308     1012    78000 SH       SOLE                  78000        0    0
MetLife, Inc.                    COMMON           59156R108    10573   280000 SH       SOLE                 280000        0    0
MSCI Inc. Class A                COMMON           55354G100    11097   405000 SH       SOLE                 405000        0    0
Microsoft Corporation            COMMON           594918104    13116   570000 SH       SOLE                 570000        0    0
M&T Bank Corporation             COMMON           55261F104     9769   115000 SH       SOLE                 115000        0    0
The Manitowoc Company, Inc.      COMMON           563571108     5559   608198 SH       SOLE                 608198        0    0
Nelnet, Inc.                     COMMON           64031N108    11905   617500 SH       SOLE                 617500        0    0
NetEase.com, Inc.                COMMON           64110W102     5330   168100 SH       SOLE                 168100        0    0
Nucor Corporation                COMMON           670346105     5742   150000 SH       SOLE                 150000        0    0
Poniard Pharmaceuticals, Inc.    COMMON           732449301      117   195344 SH       SOLE                 195344        0    0
PepsiCo, Inc.                    COMMON           713448108    18285   300000 SH       SOLE                 300000        0    0
Pfizer Inc.                      COMMON           717081103    10778   755808 SH       SOLE                 755808        0    0
PartnerRe Ltd.                   COMMON           G6852T105    19289   275000 SH       SOLE                 275000        0    0
QUALCOMM Incorporated            COMMON           747525103    22988   700000 SH       SOLE                 700000        0    0
Everest Re Group, Ltd.           COMMON           G3223R108    18387   260000 SH       SOLE                 260000        0    0
Republic Services, Inc.          COMMON           760759100    28214   949000 SH       SOLE                 949000        0    0
Royce Value Trust, Inc.          COMMON           780910105     1532   144955 SH       SOLE                 144955        0    0
Symetra Financial Corporation    COMMON           87151Q106     2400   200000 SH       SOLE                 200000        0    0
Teradata Corporation             COMMON           88076W103    13716   450000 SH       SOLE                 450000        0    0
The TJX Companies, Inc.          COMMON           872540109    68479  1632400 SH       SOLE                1632400        0    0
Transatlantic Holdings, Inc.     COMMON           893521104     3981    83000 SH       SOLE                  83000        0    0
The Travelers Companies, Inc.    COMMON           89417E109     9850   200000 SH       SOLE                 200000        0    0
Textron Inc.                     COMMON           883203101     3649   215000 SH       SOLE                 215000        0    0
United Technologies Corporation  COMMON           913017109    21096   325000 SH       SOLE                 325000        0    0
Verifone Holdings, Inc. 1 3/8%   NOTE             92342YAB5     9250 10000000 PRN      SOLE               10000000        0    0
Weatherford International Ltd.   COMMON           G95089101    28251  2150000 SH       SOLE                2150000        0    0
Waste Management, Inc.           COMMON           94106L109    19713   630000 SH       SOLE                 630000        0    0
Wal-Mart Stores, Inc.            COMMON           931142103    26439   550000 SH       SOLE                 550000        0    0
Xerox Corporation                COMMON           984121103    15276  1900000 SH       SOLE                1900000        0    0