UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                   FORM 13F

                             FORM 13F COVER PAGE

Report for the Calendar Year or Quarter Ended: December 31, 2006

Check here if Amendment [ ]; Amendment Number:
This Amendment (Check only one.): [ ] is a restatement.
                                  [ ] adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:GENERAL AMERICAN INVESTORS COMPANY, INC.
Address: 450 Lexington Ave, Suite 3300
         New York, NY 10017

13F File Number: 28-461

The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.




Person Signing this Report on Behalf of Reporting Manager:

Name: Eugene S. Stark
Title: Vice-President, Administration
Phone: 212-916-8447
Signature, Place, and Date of Signing:

  /s/Eugene S. Stark   New York, NY   February 09, 2007


Report Type (Check only one.):

[X]    13F HOLDINGS REPORT.

[ ]    13F NOTICE.

[ ]    13F COMBINATION REPORT.



FORM 13F SUMMARY PAGE


Report Summary:

Number of Other Included Managers:       0

Form 13F Information Table Entry Total:  59

Form 13F Information Table Value Total:  $1332807138



List of Other Included Managers:

No.   13F File Number    Name
NONE




   COLUMN 1                           COLUMN 2     COLUMN 3  COLUMN 4      COLUMN 5    COLUMN 6  COLUMN 7         COLUMN 8
 --------------                      ---------    ---------  -------- -------------    --------  --------    ------------------
                                                             VALUE    SHARES/ SH/ PUT/ INVSTMT   OTHER    -----VOTING AUTHORITY-----
  NAME OF ISSUER                 -TITLE OF CLASS- --CUSIP-- x$1000    PRN AMT PRN CALL DSCRETN -MANAGERS-     SOLE   SHARED     NONE
                                                                                                      
ABB Ltd. ADR                     COMMON           000375204    20677  1150000 SH       SOLE                1150000        0        0
Arch Capital Group Ltd.          COMMON           G0450A105    23664   350000 SH       SOLE                 350000        0        0
Adams Express Company            COMMON           006212104     1537   110806 SH       SOLE                 110806        0        0
American International Group,Inc COMMON           026874107    25798   360000 SH       SOLE                 360000        0        0
Alkermes, Inc.                   COMMON           01642T108     2340   175000 SH       SOLE                 175000        0        0
The Allstate Corporation         COMMON           020002101    17905   275000 SH       SOLE                 275000        0        0
Ameriprise Financial, Inc.       COMMON           03076C106     3270    60000 SH       SOLE                  60000        0        0
American Tower Corporation       COMMON           029912201    28892   775000 SH       SOLE                 775000        0        0
Apache Corporation               COMMON           037411105    54871   825000 SH       SOLE                 825000        0        0
Activision, Inc.                 COMMON           004930202    12068   700000 SH       SOLE                 700000        0        0
Avaya Inc.                       COMMON           053499109     7759   555000 SH       SOLE                 555000        0        0
AXIS Capital Holdings Limited    COMMON           G0692U109    13348   400000 SH       SOLE                 400000        0        0
Bank of America Corporation      COMMON           060505104    14415   270000 SH       SOLE                 270000        0        0
Biogen Idec Inc.                 COMMON           09062X103     8362   170000 SH       SOLE                 170000        0        0
Berkshire Hathaway Inc. Class A  COMMON           084670108    32997      300 SH       SOLE                    300        0        0
Cephalon, Inc.                   COMMON           156708109    10562   150000 SH       SOLE                 150000        0        0
Central Securities Corporation   COMMON           155123102      752    28226 SH       SOLE                  28226        0        0
Costco Wholesale Corporation     COMMON           22160K105    37009   700000 SH       SOLE                 700000        0        0
Cisco Systems, Inc.              COMMON           17275R102    24597   900000 SH       SOLE                 900000        0        0
CEMEX, S.A. de C.V. ADR          COMMON           151290889    79647  2350862 SH       SOLE                2350862        0        0
Cytokinetics, Incorporated       COMMON           23282W100     4525   604900 SH       SOLE                 604900        0        0
Diageo plc ADR                   COMMON           25243Q205    27759   350000 SH       SOLE                 350000        0        0
Dollar General Corporation       COMMON           256669102    40150  2500000 SH       SOLE                2500000        0        0
Genentech, Inc.                  COMMON           368710406    16226   200000 SH       SOLE                 200000        0        0
EMC Corporation                  COMMON           268648102     3960   300000 SH       SOLE                 300000        0        0
Halliburton Company              COMMON           406216101    26393   850000 SH       SOLE                 850000        0        0
The Home Depot, Inc.             COMMON           437076102    63051  1570000 SH       SOLE                1570000        0        0
Intermec, Inc.                   COMMON           458786100     2306    95000 SH       SOLE                  95000        0        0
Lamar Advertising Company        COMMON           512815101    22887   350000 SH       SOLE                 350000        0        0
Medtronic, Inc.                  COMMON           585055106    24080   450000 SH       SOLE                 450000        0        0
MedImmune, Inc.                  COMMON           584699102    12301   380000 SH       SOLE                 380000        0        0
MetLife, Inc.                    COMMON           59156R108    16818   285000 SH       SOLE                 285000        0        0
MFA Mortgage Investments, Inc.   COMMON           55272X102     7113   925000 SH       SOLE                 925000        0        0
Molex Incorporated Class A       COMMON           608554200    15235   550000 SH       SOLE                 550000        0        0
Microsoft Corporation            COMMON           594918104    21499   720000 SH       SOLE                 720000        0        0
M&T Bank Corporation             COMMON           55261F104    37870   310000 SH       SOLE                 310000        0        0
Annaly Capital Management, Inc.  COMMON           035710409     7651   550000 SH       SOLE                 550000        0        0
NetEase.com, Inc.                COMMON           64110W102     3738   200000 SH       SOLE                 200000        0        0
PepsiCo, Inc.                    COMMON           713448108    14074   225000 SH       SOLE                 225000        0        0
Pfizer Inc                       COMMON           717081103    34911  1347900 SH       SOLE                1347900        0        0
PartnerRe Ltd.                   COMMON           G6852T105    23795   335000 SH       SOLE                 335000        0        0
Patterson-UTI Energy, Inc.       COMMON           703481101    23230  1000000 SH       SOLE                1000000        0        0
QUALCOMM Incorporated            COMMON           747525103    26453   700000 SH       SOLE                 700000        0        0
Everest Re Group, Ltd.           COMMON           G3223R108    49055   500000 SH       SOLE                 500000        0        0
Republic Services, Inc.          COMMON           760759100    47787  1175000 SH       SOLE                1175000        0        0
Rio Tinto plc ADR                COMMON           767204100    13812    65000 SH       SOLE                  65000        0        0
Royce Value Trust                COMMON           780910105     2433   109547 SH       SOLE                 109547        0        0
Sprint Nextel Corporation        COMMON           852061100    13884   735000 SH       SOLE                 735000        0        0
SunTrust Banks, Inc.             COMMON           867914103    14357   170000 SH       SOLE                 170000        0        0
Constellation Brands, Inc.       COMMON           21036P108     9432   325000 SH       SOLE                 325000        0        0
THQ Inc.                         COMMON           872443403     6992   215000 SH       SOLE                 215000        0        0
The TJX Companies, Inc.          COMMON           872540109    59892  2100000 SH       SOLE                2100000        0        0
Talisman Energy Inc.             COMMON           87425E103    50970  3000000 SH       SOLE                3000000        0        0
Transatlantic Holdings, Inc.     COMMON           893521104    14283   230000 SH       SOLE                 230000        0        0
VeriSign, Inc.                   COMMON           92343E102     2730   113500 SH       SOLE                 113500        0        0
Wachovia Corporation             COMMON           929903102    35017   614864 SH       SOLE                 614864        0        0
Weatherford International Ltd.   COMMON           G95089101    50984  1220000 SH       SOLE                1220000        0        0
Wal-Mart Stores, Inc.            COMMON           931142103    26554   575000 SH       SOLE                 575000        0        0
Xerox Corporation                COMMON           984121103    38138  2250000 SH       SOLE                2250000        0        0