UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM N-CSR

                   CERTIFIED SHAREHOLDER REPORT OF REGISTERED
                         MANAGEMENT INVESTMENT COMPANIES

                 Investment Company Act file number: 811-00041
                 ---------------------------------------------

                    GENERAL AMERICAN INVESTORS COMPANY, INC.

--------------------------------------------------------------------------------
               (Exact name of registrant as specified in charter)

         450 Lexington Avenue, Suite 3300, New York, New York 10017-3911
--------------------------------------------------------------------------------
               (Address of principal executive offices) (Zip code)

                                Eugene S. Stark
                    General American Investors Company, Inc.
                            450 Lexington Avenue
                                Suite 3300
                       New York, New York  10017-3911
                  (Name and address of agent for service)

                                    Copy to:
                           John E. Baumgardner, Jr., Esq.
                             Sullivan & Cromwell LLP
                                125 Broad Street
                            New York, New York 10004


        Registrant's telephone number, including area code: 212-916-8400

Date of fiscal year end:  December 31

Date of reporting period: December 31, 2005

 2
ITEM 1.  REPORTS TO STOCKHOLDERS.


                                     GENERAL
                                     AMERICAN
                                    INVESTORS

                                      2005
                                     ANNUAL
                                     REPORT

 3
                    GENERAL AMERICAN INVESTORS COMPANY, INC.

Established  in 1927, the Company is a closed-end  investment  company listed on
the New York Stock  Exchange.  Its objective is long-term  capital  appreciation
through investment in companies with above average growth potential.



   FINANCIAL SUMMARY (unaudited)
-------------------------------------------------------------------------------------
                                                      2005                   2004
                                                 -------------         --------------
                                                                 
   Net assets applicable to Common Stock -
      December 31                               $1,132,941,654         $1,036,393,093
   Net investment income                             5,408,018              9,253,481
   Net realized gain                                63,024,095             36,774,029
   Net increase in unrealized appreciation         103,638,830             62,361,773
   Distributions to Preferred Stockholders        (11,900,000)           (11,900,000)

   Per Common Share-December 31
      Net asset value                                   $39.00                 $35.49
      Market price                                      $34.54                 $31.32
   Discount from net asset value                        -11.4%                 -11.7%

   Common Shares outstanding-Dec. 31                29,050,399             29,205,312
   Common Stockholders of record-Dec. 31                 4,100                  4,300
   Market price range* (high-low)                $35.45-$29.37          $31.74-$27.88
   Market volume-shares                              7,242,000              6,206,400
   *Unadjusted for dividend payments.



   DIVIDEND SUMMARY (per share) (unaudited)
-------------------------------------------------------------------------------------
                                               Ordinary        Long-Term
   Record Date             Payment Date         Income        Capital Gain     Total
   ------------            ------------       ---------       ------------   --------
   Common Stock
                                                                  
   Nov. 11, 2005           Dec. 22, 2005    $.587543 (a)       $1.260182      $1.847725
   Jan. 30, 2006           Feb. 13, 2006        -                .138000        .138000
                                            --------           ---------      ---------
      Total from 2005 earnings              $.587543           $1.398182      $1.985725
                                            ========           =========      =========

   Nov. 12, 2004           Dec. 23, 2004    $.215327            $.684673       $.900000
   Jan. 31, 2005           Mar. 10, 2005     .002000             .272000        .274000
                                            --------            --------      ---------
      Total from 2004 earnings              $.217327            $.956673      $1.174000
                                            ========            ========      =========
         (a) Includes short-term gain in the amount of $.041294 per share.

   Preferred Stock

   Mar. 7, 2005            Mar. 24, 2005    $.102969            $.268906       $.371875
   Jun. 7, 2005            Jun. 24, 2005     .102969             .268906        .371875
   Sep. 7, 2005            Sep. 26, 2005     .102969             .268906        .371875
   Dec. 7, 2005            Dec. 27, 2005     .102969             .268906        .371875
                                            --------           ---------      ---------
      Total for 2005                        $.411876 (b)       $1.075624      $1.487500
                                            ========           =========      =========

   Mar. 8, 2004            Mar. 24, 2004    $.083947            $.287928       $.371875
   Jun. 7, 2004            Jun. 24, 2004     .083947             .287928        .371875
   Sep. 7, 2004            Sep. 24, 2004     .083947             .287928        .371875
   Dec. 7, 2004            Dec. 27, 2004     .083947             .287928        .371875
                                            --------           ---------      ---------
      Total for 2004                        $.335788           $1.151712      $1.487500
                                            ========           =========      =========
         (b) Includes short-term gain in the amount of $.028844 ($.007211 per quarter).


                    General American Investors Company, Inc.
                    450 Lexington Avenue, New York, NY 10017
                          (212) 916-8400 (800) 436-8401
                       E-mail: InvestorRelations@gainv.com
                        www.generalamericaninvestors.com
 4

1   TO THE STOCKHOLDERS
--------------------------------------------------------------------------------
    General American Investors

The U.S. stock market rose for the third consecutive  year,  gaining 4.8% in the
12 months ended December 31, 2005, as measured by our benchmark,  the Standard &
Poor's 500 Stock Index (including income). General American Investors' net asset
value (NAV) per Common Share (assuming  reinvestment of all dividends) increased
16.2%.  The return to our Common  Stockholders  was 17.4%,  reflecting  a slight
narrowing in the  discount at which our shares  trade,  which,  at year end, was
11.4%.

The table that follows,  which compares our returns on an annualized  basis with
the S&P 500,  illustrates  that over many years  General  American  has produced
superior investment results.

Years        Stockholder Return      S&P 500
---------------------------------------------
  3                 17.5%             14.3%
  5                  4.3               0.5
 10                 16.4               9.0
 20                 14.8              11.9
 30                 17.4              12.7
 40                 12.9              10.3

The share repurchase  program,  a part of our continuing effort to maximize NAV,
continues  apace.  During 2005,  the Company  purchased  1,222,404 of its Common
Shares in the open market at an average  discount to NAV of 12.4%.  The Board of
Directors has authorized repurchases of Common Shares when they are trading at a
discount in excess of 8% of NAV.

Markets  rallied  again  last  year,  continuing  the trend  that began in 2003.
Earnings rose  meaningfully,  and interest rates  remained at relatively  modest
levels by historic  standards,  notwithstanding the Federal  Reserve's  ongoing
tightening  campaign.  While mirroring  economic  trends,  the relatively  muted
performance of stocks reflected the compression in valuation multiples (price to
earnings ratios) that generally attends a maturing business cycle.

Our performance last year benefited importantly from the portfolio's exposure to
the shares of oil and natural gas producers and their service  providers.  Other
contributors  included financial services,  biotech and cement companies.  As in
the past,  our  investments  were  focused on  companies  with strong  financial
characteristics  and powerful  positions in growing  industries.  Both operating
costs relative to average net assets and portfolio  turnover remained well below
the equity mutual fund industry norm.

We enter 2006 with cautious optimism, encouraged by robust global growth and the
resiliency of our economy in the face of rising interest rates and higher energy
costs.  While there is currently  little evidence of decelerating  spending,  we
fear that consumer demand for durables like cars and housing is unlikely to rise
appreciably.  It would appear that  consumers  have been spending more than they
make for some time,  while other sources of  liquidity,  like home equity loans,
will  probably  contract,  even  assuming  that the Fed stops raising rates this
year. With the unemployment rate below 5% and labor shortages,  especially among
skilled workers,  increasingly common, corporations may well supplement flagging
consumer  demand with increased  expenditure on  productivity-enhancing  capital
goods. They have been reluctant  spenders in this business cycle,  continuing to
cut  costs  and  rationalize   facilities  in  the  face  of  lower-cost   Asian
competition.

As corporate earnings have continued to grow, market valuations have become more
reasonable,  but  not  generally  compelling.  Inflation  appears  to be  rising
steadily, if not spectacularly,  which together with an aging economic expansion
may continue to pressure the multiple awarded earnings and, consequently, market
prices.  We  remain  encouraged,   however,   by  the  earnings  and  cash  flow
characteristics  of our portfolio  companies and highly confident that our staff
will continue to perform to its customary high standard.

As mentioned in the mid-year report, Eugene L. DeStaebler,  Jr., who had been an
officer  of  the  Company   for  thirty   years,   retired  as   Vice-President,
Administration,  on June 30, 2005.  Mr.  DeStaebler  continued to serve as Chief
Compliance Officer, under a consultancy arrangement,  through December 31, 2005.
Effective  January 1, 2006,  Eugene S.  Stark,  Vice-President,  Administration,
assumed the additional responsibilities of Chief Compliance Officer.

We are pleased to report that on December  14, 2005,  Dr.  Sally Lynch,  who has
been employed as a securities  analyst at the Company since 1997,  and Mr. Jesse
Stuart, CFA, who has also been employed as a securities analyst since 2003, were
appointed Vice-Presidents of the Company, both effective January 1, 2006.

We are saddened to report that Dr. William O. Baker, our esteemed  colleague and
Director Emeritus,  died on October 31, 2005. Dr. Baker, a prominent  scientist,
former  Chairman  of the  Board of Bell  Laboratories,  and an  adviser  to five
presidents  on  scientific  affairs,  served as a director of the Company for 13
years,  and as Director  Emeritus  since 1996.  His counsel and support  will be
missed.

Information about the Company,  including our investment  objectives,  operating
policies  and  procedures,  investment  results,  record of  dividend  payments,
financial reports and press releases,  etc., is available on our website,  which
can be accessed at www.generalamericaninvestors.com.

By Order of the Board of Directors,

Spencer Davidson
President and Chief Executive Officer
January 18, 2006
 5


2  THE COMPANY
-------------------------------------------------------------------------------
   General American Investors

CORPORATE OVERVIEW

General American  Investors,  established in 1927, is one of the nation's oldest
closed-end investment companies. It is an independent  organization,  internally
managed.  For regulatory  purposes,  the Company is classified as a diversified,
closed-end  management investment company; it is registered under and subject to
the regulatory provisions of the Investment Company Act of 1940.

INVESTMENT POLICY

The primary objective of the Company is long-term capital  appreciation.  Lesser
emphasis  is placed on  current  income.  In  seeking  to  achieve  its  primary
objective,  the Company  invests  principally  in common stocks  believed by its
management to have better than average growth potential.

The Company's investment approach focuses on the selection of individual stocks,
each of which is  expected  to meet a clearly  defined  portfolio  objective.  A
continuous  investment  research program,  which stresses  fundamental  security
analysis,  is  carried on by the  officers  and staff of the  Company  under the
oversight  of the Board of  Directors.  A listing  of the  directors  with their
principal  affiliations,  showing a broad range of  experience  in business  and
financial affairs, is on page 20.

PORTFOLIO MANAGER

Mr.  Spencer  Davidson  has  been  responsible  for the  management  of  General
American's  portfolio since he was elected President and Chief Executive Officer
of the Company in August 1995. Mr.  Davidson,  who joined the Company in 1994 as
senior investment counselor, has spent his entire business career on Wall Street
since first joining an investment and banking firm in 1966.

"GAM" Common Stock

As a closed-end  investment  company,  General American Investors does not offer
its  shares  continuously.  The  Common  Stock is listed  on The New York  Stock
Exchange (symbol, GAM) and can be bought or sold with commissions  determined in
the same manner as all listed stocks.  Net asset value is computed and published
on the  Company's  website daily (on an unaudited  basis) and is furnished  upon
request.  It is also available on most electronic  quotation  services using the
symbol  "XGAMX."  The figure for net asset  value per share,  together  with the
market price and the  percentage  discount or premium from net asset value as of
the close of each week,  is  published  in The New York  Times,  The Wall Street
Journal and Barron's.

The ratio of market  price to net asset value has shown  considerable  variation
over a long period of time.  While shares of GAM usually sell at a discount from
their underlying net asset value, as do the shares of most other domestic equity
closed-end investment companies, they, occasionally,  sell at a premium over net
asset value. During 2005, the stock sold at discounts from net asset value which
ranged from 9.8%  (November  9) to 14.9% (July 5). At December  31, the price of
the stock was at a discount of 11.4% as compared with a discount of 11.7% a year
earlier.

"GAM Pr B" Preferred Stock

On September 24, 2003, the Company issued and sold in an  underwritten  offering
8,000,000  shares  of its  5.95%  Cumulative  Preferred  Stock,  Series B with a
liquidation preference of $25 per share ($200,000,000 in the aggregate).

The Preferred  Shares are  noncallable  for 5 years,  are rated "aaa" by Moody's
Investors Service, Inc. and are listed and traded on The New York Stock Exchange
(symbol,  GAM Pr B). preferred  capital is available to leverage the investment
 6
3  THE COMPANY
--------------------------------------------------------------------------------
   General American Investors

performance of the Common Stockholders.  As is the case for leverage in general,
it may also result in higher market volatility for the Common Stockholders.

DIVIDEND AND DISTRIBUTION POLICY

The Company's dividend and distribution  policy is to distribute to stockholders
before year-end  substantially  all ordinary income  estimated for the full year
and capital gains realized during the ten-month  period ended October 31 of that
year. If any additional  capital gains are realized or ordinary income is earned
during the last two months of the year,  a  "spill-over"  distribution  of these
amounts  will be paid  early  in the  following  year  to  Common  Stockholders.
Dividends and  distributions  on shares of Preferred  Stock are paid  quarterly.
Distributions  from  capital  gains  and  dividends  from  ordinary  income  are
allocated  proportionately among holders of shares of Common Stock and Preferred
Stock.

Dividends from income have been paid continuously on the Common Stock since 1939
and capital gain distributions in varying amounts have been paid for each of the
years  1943-2005  (except for the year 1974).  (A table  listing  dividends  and
distributions paid during the 20-year period 1986-2005 is shown at the bottom of
page 6.) To the extent that shares can be issued,  dividends  and  distributions
are paid to Common  Stockholders in additional shares of Common Stock unless the
stockholder  specifically  requests  payment in cash.  Spill-over  dividends and
distributions of nominal amounts may be paid in cash only.

PROXY VOTING POLICIES, PROCEDURES AND RECORD

The policies and procedures used by General American  Investors to determine how
to vote proxies relating to portfolio  securities and the Company's proxy voting
record for the 12-month  period ended June 30, 2005 are  available:  (1) without
charge,   upon  request,   by  calling  the  Company  at  its  toll-free  number
(1-800-436-8401),       (2)      on      the      Company's      website      at
www.generalamericaninvestors.com   and  (3)  on  the   Securities  and  Exchange
Commission's website at www.sec.gov.

DIRECT REGISTRATION

The Company makes available  direct  registration  for its Common  Shareholders.
Direct  registration,   which  is  an  element  of  the  Investors  Choice  Plan
administered  by our  transfer  agent,  is a system that  allows for  book-entry
ownership and the electronic  transfer of our Common Shares.  Accordingly,  when
Common  Shareholders,  who  hold  their  shares  directly,  receive  new  shares
resulting  from a purchase,  transfer or dividend  payment,  they will receive a
statement showing the credit of the new shares as well as their Plan account and
certificated  share  balances.  A brochure  which  describes  the  features  and
benefits of the Investors Choice Plan,  including the ability of shareholders to
deposit  certificates  with our  transfer  agent,  can be  obtained  by  calling
American Stock Transfer & Trust Company at  1-800-413-5499,  calling the Company
at  1-800-436-8401 or visiting our website:  www.generalamericaninvestors.com  -
click on Dividends & Reports, then Report Downloads.

PRIVACY POLICY AND PRACTICES

General American Investors  collects  nonpublic  personal  information about its
customers  (stockholders)  with respect to their  transactions  in shares of the
Company's securities but only for those stockholders whose shares are registered
in their  names.  This  information  includes  the  stockholder's  address,  tax
identification or Social Security number and dividend elections.  We do not have
knowledge of, nor do we collect  personal  information  about,  stockholders who
hold the Company's securities at financial institutions such as brokers or banks
in "street name" registration.

We do not disclose any nonpublic personal  information about our stockholders or
former stockholders to anyone, except as permitted by law.

We restrict access to nonpublic  personal  information about our stockholders to
those  employees who need to know that  information  to provide  services to our
stockholders.  We maintain physical,  electronic and procedural  safeguards that
comply with federal  standards  to guard our  stockholders'  nonpublic  personal
information.
 7
4  INVESTMENT RESULTS  (UNAUDITED)
--------------------------------------------------------------------------------
   General American Investors

"Total return on $10,000 investment 20 years ended December 31, 2005"


The investment  return for a Common  Stockholder of General  American  Investors
(GAM) over the 20 years ended  December 31, 2005 is shown in the table below and
in the accompanying chart. The return based on GAM's net asset value (NAV) per
Common  Share in  comparison  to the  change in the  Standard & Poor's 500 Stock
Index (S&P 500) is also displayed.  Each  illustration  assumes an investment of
$10,000 at the beginning of 1986.

THE  STOCKHOLDER  RETURN is the return a Common  Stock  holder of GAM would have
achieved assuming  reinvestment of all dividends and distributions at the actual
reinvestment  price and of all cash  dividends at the average (mean between high
and low) market price on the ex-dividend date.

THE GAM NET ASSET  VALUE (NAV)  RETURN is the return on shares of the  Company's
Common  Stock  based on the NAV per share,  including  the  reinvestment  of all
dividends and distributions.

THE  S&P  500  RETURN  is  the  time-weighted  total  rate  of  return  on  this
widely-recognized,  unmanaged  index which is a measure of general  stock market
performance, including dividend income.

The  results  illustrated  are a  record  of  past  performance  and  may not be
indicative of future results.



                              GENERAL AMERICAN INVESTORS
              -------------------------------------------------------     STANDARD & POOR'S 500
                 STOCKHOLDER RETURN         NET ASSET VALUE RETURN                RETURN
              ------------------------    ---------------------------   ------------------------------
              CUMULATIVE       ANNUAL       CUMULATIVE      ANNUAL       CUMULATIVE          ANNUAL
              INVESTMENT       RETURN       INVESTMENT      RETURN       INVESTMENT          RETURN
             -------------------------    ---------------------------   ------------------------------
                                                                           
     1986       $11,117         11.17%        $11,117        11.17%        $11,869            18.69%
     1987         9,326        -16.11          11,398         2.53          12,491             5.24
     1988        11,309         21.26          13,401        17.57          14,556            16.53
     1989        16,805         48.60          18,475        37.86          19,158            31.62
     1990        17,477          4.00          19,710         6.69          18,566            -3.09
     1991        32,332         85.00          31,752        61.09          24,210            30.40
     1992        37,111         14.78          32,879         3.55          26,048             7.59
     1993        31,203        -15.92          32,303        -1.75          28,684            10.12
     1994        28,751         -7.86          31,418        -2.74          29,048             1.27
     1995        34,851         21.22          38,827        23.58          39,941            37.50
     1996        41,640         19.48          46,580        19.97          49,092            22.91
     1997        59,371         42.58          61,509        32.05          65,454            33.33
     1998        77,960         31.31          83,124        35.14          84,141            28.55
     1999       108,536         39.22         113,381        36.40         101,777            20.96
     2000       129,266         19.10         133,381        17.64          92,526            -9.09
     2001       134,864          4.33         131,781        -1.20          81,525           -11.89
     2002        98,167        -27.21         101,445       -23.02          63,475           -22.14
     2003       124,682         27.01         129,241        27.40          81,603            28.56
     2004       135,642          8.79         142,643        10.37          90,408            10.79
     2005       159,243         17.40         165,751        16.20          94,775             4.83

 8
5   INVESTMENT RESULTS  (UNAUDITED)
--------------------------------------------------------------------------------
    General American Investors

[CAPTION]
[Line  graph  with  heading  "20-YEAR  INVESTMENT  RESULTS  ASSUMING  AN INITIAL
INVESTMENT OF $10,000" at top left hand side.  The vertical axis is to the right
side of the page and is labeled "CUMULATIVE VALUE OF INVESTMENT." The axis range
is from $0 to $180,000 in $20,000 increments. The horizontal axis, on the bottom
of the page,  consists of the years 1986  through  2005 in one year  increments.
Within the graph are three  lines.  The first line  represents  GAM  Stockholder
Return.  The second line  represents  GAM Net Asset Value Return,  and the third
line  represents the return of the S&P 500 Stock Index.  The data points for the
lines are derived  from the columns  labeled  "Cumulative  Investment"  from the
table on the preceding page.  Also,  embedded in upper left portion of the graph
is a table which appears as follows:]



         COMPARATIVE ANNUALIZED INVESTMENT RESULTS
         -----------------------------------------
    YEARS ENDED         STOCKHOLDER      GAM NET       S&P 500
 DECEMBER 31, 2005         RETURN       ASSET VALUE   STOCK INDEX
------------------------------------------------------------------
                                                
     1 year                17.4%          16.2%           4.8%
     5 years                4.3            4.4            0.5
    10 years               16.4           15.6            9.0
    15 years               15.9           15.3           11.5
    20 years               14.8           15.1           11.9

 9
6  MAJOR STOCK CHANGES*: THREE MONTHS ENDED DECEMBER 31, 2005 (UNAUDITED)
--------------------------------------------------------------------------------
   General American Investors




                                                                                SHARES HELD
INCREASES                                                       SHARES       DECEMBER 31, 2005
---------------------------------------------------------------------------------------------------
                                                                           

ADDITIONS

    Cytokinetics, Incorporated                                  54,900             604,900
    MFA Mortgage Investments, Inc.                             375,000           1,300,000
    Patterson-UTI Energy, Inc.                                 250,000           1,000,000
    Talisman Energy Inc.                                       208,700           1,000,000
    Weatherford International Ltd.                             185,000           1,220,000 (a)


DECREASES
---------------------------------------------------------------------------------------------------

ELIMINATIONS

    Central Securities Corporation                             102,809 (b)              -
    CIENA Corporation                                          550,000                  -
    Millenium Pharmaceuticals, Inc.                            120,000                  -
    Reinsurance Group of America, Incorporated                 200,000                  -
    Silicon Genesis Corporation                                144,000                  -

REDUCTIONS

    American International Group, Inc.                           5,000             345,000
    Annaly Mortgage Management, Inc.                           175,000             500,000
    Bank of America Corporation                                 35,000             280,000
    Brooks Automation, Inc.                                    168,500             323,000
    Devon Energy Corporation                                   582,000             758,000
    Everest Re Group, Ltd.                                      10,000             540,000
    Genentech, Inc.                                             35,000             330,000
    The Home Depot, Inc.                                       225,000           1,695,000
    Microsoft Corporation                                      125,000           1,400,000
    PartnerRe Ltd.                                              25,000             375,000
    Pfizer Inc                                                  50,000           1,250,000


* Excludes transactions in Stocks-Miscellaneous-Other.
(a) Includes shares received in conjunction with a stock split.
(b) Includes shares received from dividend payments.




"The following table shows aggregate  dividends and distributions paid per share
on the Company's Common Stock for each year during the 20-year period 1986-2005.
Amounts shown include  payments made after year-end  attributable  to income and
gain in each respective year."

DIVIDENDS AND DISTRIBUTIONS PER COMMON SHARE (1986-2005)  (UNAUDITED)
-------------------------------------------------------------------------------


                      EARNINGS SOURCE
                 ----------------------------
                  SHORT-TERM     LONG-TERM
   YEAR   INCOME CAPITAL GAINS  CAPITAL GAINS
----------------------------------------------
                         
   1986    $.36         -         $2.15
   1987     .35         -          1.54
   1988     .29         -          1.69
   1989     .21      $.02          1.56
   1990     .21         -          1.65
   1991     .09         -          3.07
   1992     .03         -          2.93
   1993     .06         -          2.34
   1994     .06         -          1.59
   1995     .10       .03          2.77
   1996     .20       .05          2.71
   1997     .21         -          2.95
   1998     .47         -          4.40
   1999     .42       .62          4.05
   2000     .48      1.55          6.16
   2001     .37       .64          1.37
   2002     .03         -           .33
   2003     .02         -           .59
   2004     .217        -           .957
   2005     .547      .041         1.398

 10

7  TEN LARGEST INVESTMENT HOLDINGS (UNAUDITED)
--------------------------------------------------------------------------------
   General American Investors

"The statement of investments as of December 31, 2005, shown on pages 12 and 13
includes 53 security issues.  Listed here are the ten largest holdings on that
date."




                                                                                                    % COMMON
                                                                           SHARES         VALUE     NET ASSETS*
------------------------------------------------------------------------------------------------------------------------------------
                                                                                               
THE HOME DEPOT, INC.                                                     1,695,000     $68,613,600       6.1%
The largest company in home center retailing, Home Depot's
proven merchandising capabilities and strong financial structure
should provide the basis for continuing growth.
------------------------------------------------------------------------------------------------------------------------------------
CEMEX, S.A. de C.V. ADR                                                  1,143,041      67,816,623       6.0
Domiciled in Mexico, CEMEX is the third largest cement producer
in the world.  With the expansion of its operations into related
construction materials and additional geographic areas, as well as
its focus on cost containment, the company's free cash
flow should continue to increase, supporting a positive long-term
outlook.
------------------------------------------------------------------------------------------------------------------------------------
THE TJX COMPANIES, INC.                                                  2,500,000      58,075,000       5.1
Through its T.J. Maxx and Marshalls divisions, TJX is a leading
off-price retailer. The continued growth of these divisions, along
with expansion into related U.S. and foreign off-price formats,
provide ongoing growth opportunities.
------------------------------------------------------------------------------------------------------------------------------------
EVEREST RE GROUP, LTD.                                                     540,000      54,189,000       4.8
The largest independent U.S. property/casualty reinsurer, which
generates annual premiums of approximately $4.7 billion and has
a high quality, well-reserved AA balance sheet. This Bermuda
domiciled company has a strong management team that exercises
underwriting discipline and efficient expense control,
resulting in above-average earnings growth.
------------------------------------------------------------------------------------------------------------------------------------
TALISMAN ENERGY INC.                                                     1,000,000      52,880,000       4.7
Talisman, headquartered in Calgary, Alberta, is an upstream
oil and gas producer with global operations.  The company is
focusing on larger, deep gas opportunities in North America
and large international projects which should lead to faster
production growth and higher returns.
------------------------------------------------------------------------------------------------------------------------------------
DEVON ENERGY CORPORATION                                                   758,000      47,405,320       4.2
One of the largest independent oil and gas exploration and
production companies, Devon operates both domestically and
internationally. Recent opportunistic acquisitions have enhanced
production and improved the company's exploration
profile.
------------------------------------------------------------------------------------------------------------------------------------
APACHE CORPORATION                                                         665,000      45,565,800       4.0
Apache is a large independent oil and gas company.  The
company has a long history of growing production and creating
value for shareholders.  The company's operations are primarily
focused in North America, the North Sea and Egypt.
------------------------------------------------------------------------------------------------------------------------------------
WEATHERFORD INTERNATIONAL LTD.                                           1,220,000      44,164,000       3.9
Weatherford supplies a broad range of oil field services through
its Drilling Methods, Well Construction, Drilling Tools and
Intervention Services divisions on a worldwide basis.  Its focus on
increasing production from existing fields and synergies from the
acquisition of assets from Precision Drilling should lead to
earnings growth.
------------------------------------------------------------------------------------------------------------------------------------
REPUBLIC SERVICES, INC.                                                  1,175,000      44,121,250       3.9
Republic Services is a leading provider of non-hazardous solid waste
collection and disposal services in the U.S. The efficient operation
of its routes and facilities combined with appropriate pricing enable
Republic Services to generate significant free cash flow. The high
probability of additional contracts and the expectation that
economic activity will continue to improve should result in higher
waste volumes for the company.
------------------------------------------------------------------------------------------------------------------------------------
EOG RESOURCES, INC.                                                        600,000      44,022,000       3.8
EOG is rapidly growing its reserves and production of natural gas.
The company's assets are primarily in North America and Trinidad.
The company earns among the highest returns on capital in its
industry.
------------------------------------------------------------------------------------------------------------------------------------
                                                                                        $526,852,593    46.5%
                                                                                        ============    =====

*Net assets applicable to the Company's Common Stock.
 11
8  PORTFOLIO DIVERSIFICATION (unaudited)
--------------------------------------------------------------------------------
   General American Investors

"The diversification of the Company's net assets applicable to its securities by
industry  group as of  December  31,  2005  and  2004 is shown in the  following
table."



                                                                             PERCENT COMMON NET ASSETS*
                                           DECEMBER 31, 2005                        DECEMBER 31
-----------------------------------------------------------------------------------------------------------------
INDUSTRY CATEGORY                   COST(000)            VALUE(000)            2005             2004
-----------------------------------------------------------------------------------------------------------------
                                                                                  
Oil and Natural Gas
  (Including Services)              $207,050              $335,962             29.7%           18.3%
                                    --------              --------             ----            ----
Finance and Insurance
  Banking                             18,171                99,890              8.8            10.1
  Insurance                           67,625               179,443             15.8            18.5
  Other                               16,084                12,880              1.1             2.1
                                    --------              --------             ----            ----
                                     101,880               292,213             25.7            30.7
                                    --------              --------             ----            ----
Retail Trade                          74,945               202,530             17.9            20.7
                                    --------              --------             ----            ----
Health Care
  Pharmaceuticals                     50,789                90,856              8.0            10.6
  Medical Instruments
    and Devices                       10,484                25,906              2.3             2.1
                                    --------              --------             ----            ----
                                      61,273               116,762             10.3            12.7
                                    --------              --------             ----            ----
Communications and
  Information Services                53,830                68,706              6.1             7.3
Building and Real Estate              30,441                67,817              6.0             3.9
Consumer Products and Services        62,733                66,602              5.9             3.8
Environmental Control
  (Including Services)                26,227                44,121              3.9             3.8
Computer Software and Systems         41,604                43,620              3.8             5.5
Miscellaneous**                       42,347                42,466              3.7             4.4
Technology                            25,690                27,835              2.5              -
Electronics                           12,287                13,525              1.2             1.8
Semiconductors                         4,709                 5,509              0.5             0.9
Special Holdings                       3,003                     -                -             0.1
                                    --------             ---------            -----           -----
                                     748,019             1,327,668            117.2           113.9
Short-Term securities                  3,823                 3,823              0.3             5.6
                                    --------             ---------            -----           -----
  Total investments                 $751,842             1,331,491            117.5           119.5
                                    ========             ---------            -----           -----
Cash, receivables and other
  assets less liabilities                                    1,451              0.1            (0.2)
Preferred Stock                                           (200,000)           (17.6)          (19.3)
                                                         ---------            -----           -----
Net assets applicable to
  Common Stock                                          $1,132,942            100.0%          100.0%
                                                        ==========            =====           =====

*   Net assets applicable to the Company's Common Stock.
**   Securities which have been held for less than one year, not previously disclosed and not restricted.


 12
9  STATEMENT OF ASSETS AND LIABILITIES
--------------------------------------------------------------------------------
   General American Investors


                                                                                DECEMBER 31,
                                                                     ------------------------------
ASSETS                                                                   2005              2004
---------------------------------------------------------------------------------------------------
                                                                               
INVESTMENTS, AT VALUE (NOTE 1a)
   Common and preferred stocks
      (cost $714,895,565 and $691,689,451, respectively)          $1,301,855,069     $1,167,272,723
   Corporate note (cost $33,123,366 and
      $12,326,060, respectively)                                      25,812,500         13,225,252
   Corporate discount notes (cost for 2004 $58,487,897)                        -         58,487,897
   Money Market Fund (cost for 2005 $3,822,949)                        3,822,949                  -
                                                                  --------------     --------------
   Total investments (cost $751,841,880 and
      $762,503,408, respectively)                                  1,331,490,518      1,238,985,872
CASH, RECEIVABLES AND OTHER ASSETS
   Cash                                                                   13,298            176,980
   Receivable for securities sold                                      5,733,693                  -
   Deposit with broker for securities sold short                               -          3,070,685
   Deposit with broker for options written                                     -            188,519
   Dividends, interest and other receivables                           1,028,867          1,081,136
   Prepaid pension cost                                                7,714,456          7,478,936
   Prepaid expenses and other assets                                     214,022            294,166
                                                                  --------------     --------------
TOTAL ASSETS                                                       1,346,194,854      1,251,276,294
                                                                  --------------     --------------

LIABILITIES
---------------------------------------------------------------------------------------------------
   Payable for securities purchased                                    1,468,214            411,300
   Preferred dividend accrued but not yet declared                       231,389            231,389
   Securities sold short, at value (proceeds for 2004
     $3,070,685) (note 1a)                                                     -          3,608,280
   Outstanding options written, at value (premiums
     received $188,519 for 2004) (note 1a)                                     -            123,580
   Accrued pension expense                                             5,699,484          5,484,775
   Accrued expenses and other liabilities                              5,854,113          5,023,877
                                                                  --------------     --------------
TOTAL LIABILITIES                                                     13,253,200         14,883,201
                                                                  --------------     --------------

 5.95% CUMULATIVE PREFERRED STOCK, SERIES B -
   8,000,000 shares at a liquidation value of
   $25 per share (note 2)                                            200,000,000        200,000,000
                                                                  --------------     --------------
NET ASSETS APPLICABLE TO COMMON STOCK - 29,050,399
    and 29,205,312 shares, respectively (note 2)                  $1,132,941,654     $1,036,393,093
                                                                  ==============     ==============
NET ASSET VALUE PER COMMON SHARE                                          $39.00             $35.49
                                                                  ==============     ==============

NET ASSETS APPLICABLE TO COMMON STOCK
---------------------------------------------------------------------------------------------------
    Common Stock,  29,050,399 and 29,205,312 shares at par
        value, respectively (note 2)                                 $29,050,399        $29,205,312
    Additional paid-in capital (note 2)                              518,972,693        521,985,714
    Undistributed realized gain on investments (note 2)                3,969,333          7,864,450
    Undistributed net investment income (note 2)                       1,531,980          1,559,198
    Unallocated distributions on Preferred Stock                        (231,389)          (231,389)
    Unrealized appreciation on investments, securities
        sold short and options                                       579,648,638        476,009,808
                                                                  --------------     --------------
NET ASSETS APPLICABLE TO COMMON STOCK                             $1,132,941,654     $1,036,393,093
                                                                  ==============     ==============


(see notes to financial statements)


 13
10  STATEMENT OF OPERATIONS
--------------------------------------------------------------------------------
    General American Investors



                                                                          YEAR ENDED DECEMBER 31,
                                                                         --------------------------
INCOME                                                                     2005             2004
---------------------------------------------------------------------------------------------------
                                                                                 
   Dividends (net of foreign withholding taxes
       of $490,458 and $222,175, respectively)                         $16,403,240     $18,010,297
   Interest                                                              2,318,112       2,538,401
                                                                       -----------     -----------
TOTAL INCOME                                                            18,721,352      20,548,698
                                                                       -----------     -----------

EXPENSES
---------------------------------------------------------------------------------------------------
   Investment research                                                   8,695,758       7,257,447
   Administration and operations                                         3,236,737       2,685,811
   Office space and general                                                537,671         535,685
   Directors' fees and expenses                                            218,402         187,539
   Auditing and legal fees                                                 216,600         172,200
   Transfer agent, custodian and registrar fees and expenses               176,854         179,102
   Stockholders' meeting and reports                                       129,857         169,197
   Miscellaneous taxes                                                     101,455         108,236
                                                                        ----------      ----------
TOTAL EXPENSES                                                          13,313,334      11,295,217
                                                                        ----------      ----------
NET INVESTMENT INCOME                                                    5,408,018       9,253,481
                                                                        ----------      ----------

REALIZED GAIN (LOSS) AND CHANGE IN UNREALIZED APPRECIATION ON INVESTMENTS (NOTES 1f AND 4)
------------------------------------------------------------------------------------------------------------------------------------
   Net realized gain on investments:
       Long transactions                                                63,646,612      39,187,387
       Short sale transactions (note 1b)                                  (755,114)     (2,512,348)
       Option transactions (note 1c)                                       132,597          98,990
                                                                        ----------      ----------
   Net realized gain on investments
       (long-term except for $14,501,035 for 2005)                      63,024,095      36,774,029
     Net increase in unrealized appreciation                           103,638,830      62,361,773
                                                                       -----------      ----------
NET GAIN ON INVESTMENTS                                                166,662,925       99,135,802
DISTRIBUTIONS TO PREFERRED STOCKHOLDERS                                (11,900,000)     (11,900,000)
                                                                       -----------      -----------
INCREASE IN NET ASSETS RESULTING FROM OPERATIONS                      $160,170,943      $96,489,283
                                                                      ============      ===========

(see notes to financial statements)

 14

11  STATEMENT OF CHANGES IN NET ASSETS
--------------------------------------------------------------------------------
    General American Investors




                                                                           YEAR ENDED DECEMBER 31,
                                                                      -----------------------------
OPERATIONS                                                                 2005            2004
---------------------------------------------------------------------------------------------------
                                                                               
   Net investment income                                                $5,408,018       $9,253,481
   Net realized gain on investments                                     63,024,095       36,774,029
   Net increase in unrealized appreciation                             103,638,830       62,361,773
                                                                       -----------      -----------
                                                                       172,070,943      108,389,283
                                                                       -----------      -----------

   Distributions to Preferred Stockholders:
      From net income                                                     (845,368)      (2,686,304)
      From short-term capital gains                                     (2,449,640)               -
      From long-term capital gains                                      (8,604,992)      (9,213,696)
                                                                       -----------      -----------
      Decrease in net assets from Preferred distributions              (11,900,000)     (11,900,000)
                                                                       -----------      -----------
INCREASE IN NET ASSETS RESULTING FROM OPERATIONS                       160,170,943       96,489,283
                                                                       -----------      -----------
DISTRIBUTIONS TO COMMON STOCKHOLDERS
---------------------------------------------------------------------------------------------------
   From net income                                                      (4,333,771)      (6,602,940)
   From short-term capital gains                                       (12,389,129)              -
   From long-term capital gains                                        (43,672,026)     (22,647,281)
                                                                       -----------      -----------
DECREASE IN NET ASSETS FROM COMMON DISTRIBUTIONS                       (60,394,926)     (29,250,221)
                                                                       -----------      -----------

CAPITAL SHARE TRANSACTIONS (NOTE 2)
---------------------------------------------------------------------------------------------------
   Value of Common Shares issued in payment of distributions            36,584,716       15,781,952
   Cost of Common Shares purchased                                     (39,812,172)     (32,963,032)
                                                                       -----------      -----------
DECREASE IN NET ASSETS - CAPITAL TRANSACTIONS                           (3,227,456)     (17,181,080)
                                                                       -----------      -----------
NET INCREASE  IN NET ASSETS                                             96,548,561       50,057,982

NET ASSETS APPLICABLE TO COMMON STOCK
---------------------------------------------------------------------------------------------------
BEGINNING OF YEAR                                                    1,036,393,093      986,335,111
                                                                    --------------   --------------
end of year (including undistributed net investment income of
   $1,531,980 and $1,559,198, respectively)                         $1,132,941,654   $1,036,393,093
                                                                    ==============   ==============

(see notes to financial statements)

 15


12  STATEMENT OF INVESTMENTS DECEMBER 31, 2005
--------------------------------------------------------------------------------
    General American Investors




                        SHARES    COMMON AND PREFERRED STOCKS                                     VALUE (NOTE 1a)
-----------------------------------------------------------------------------------------------------------------
                                                                                          

BUILDING AND            1,143,041 CEMEX, S.A. de C.V. ADR               (COST  $30,440,830)        $67,816,623
REAL ESTATE (6.0%)                                                                                  ----------
--------------------------------------------------------------------------------------------------------------
COMMUNICATIONS AND        675,000 American Tower Corporation (a)                                    18,292,500
INFORMATION SERVICES      900,000 Cisco Systems, Inc. (a)                                           15,408,000
(6.1%)                    350,000 Lamar Advertising Company Class A (a)                             16,145,500
                        4,600,000 Telecom Corporation of New Zealand Limited                        18,860,000
                                                                                                    ----------
                                                                        (COST  $53,829,770)         68,706,000
                                                                                                    ----------
--------------------------------------------------------------------------------------------------------------
COMPUTER SOFTWARE         300,000 EMC Corporation (a)                                                4,086,000
AND SYSTEMS (3.8%)      1,400,000 Microsoft Corporation                                             36,610,000
                          133,500 VeriSign, Inc. (a)                                                 2,923,650
                                                                                                    ----------
                                                                        (COST  $41,604,314)         43,619,650
                                                                                                    ----------
--------------------------------------------------------------------------------------------------------------
CONSUMER PRODUCTS         350,000 Diageo plc ADR                                                    20,405,000
AND SERVICES (3.6%)       275,000 Ethan Allen Interiors Inc.                                        10,045,750
                          175,000 PepsiCo, Inc.                                                     10,339,000
                                                                                                    ----------
                                                                         (COST $29,609,424)         40,789,750
                                                                                                    ----------
--------------------------------------------------------------------------------------------------------------
ELECTRONICS (1.2%)        550,000 Molex Incorporated Class A             (COST $12,287,441)         13,524,500
                                                                                                    ----------
--------------------------------------------------------------------------------------------------------------
ENVIRONMENTAL CONTROL   1,175,000 Republic Services, Inc.                (COST $26,227,380)         44,121,250
(INCLUDING SERVICES)                                                                                ----------
(3.9%)
--------------------------------------------------------------------------------------------------------------
FINANCE AND INSURANCE    BANKING (8.8%)
(25.7%)                  -------------------------------------------------------------------------------------
                          280,000 Bank of America Corporation                                       12,922,000
                          585,000 Golden West Financial Corporation                                 38,610,000
                          310,000 M&T Bank Corporation                                              33,805,500
                          200,000 SunTrust Banks, Inc.                                              14,552,000
                                                                                                    ----------
                                                                         (COST $18,170,793)         99,889,500
                                                                                                    ----------
                         INSURANCE (15.8%)
                         -------------------------------------------------------------------------------------
                          345,000 American International Group, Inc.                                23,539,350
                          500,000 Annuity and Life Re (Holdings), Ltd. (a)                             575,000
                          350,000 Arch Capital Group Ltd. (a)                                       19,162,500
                              300 Berkshire Hathaway Inc. Class A (a)                               26,586,000
                          540,000 Everest Re Group, Ltd.                                            54,189,000
                          285,000 MetLife, Inc.                                                     13,965,000
                          375,000 PartnerRe Ltd.                                                    24,626,250
                          250,000 Transatlantic Holdings, Inc.                                      16,800,000
                                                                                                   -----------
                                                                         (COST $67,625,042)        179,443,100
                                                                                                   -----------
                         OTHER (1.1%)
                         -------------------------------------------------------------------------------------
                          500,000 Annaly Mortgage Management, Inc.                                   5,470,000
                        1,300,000 MFA Mortgage Investments, Inc.                                     7,410,000
                                                                                                     ---------
                                                                         (COST $16,084,154)         12,880,000
                                                                                                    ----------
                                                                        (COST $101,879,989)        292,212,600
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
HEALTH CARE (10.3%)      PHARMACEUTICALS (8.0%)
                         -------------------------------------------------------------------------------------
                          265,000 Alkermes, Inc. (a)                                                 5,066,800
                          180,000 Biogen Idec Inc. (a)                                               8,150,400
                          604,900 Cytokinetics, Incorporated (a)                                     3,956,046
                          330,000 Genentech, Inc. (a)                                               30,525,000
                          400,000 MedImmune, Inc. (a)                                               14,008,000
                        1,250,000 Pfizer Inc                                                        29,150,000
                                                                                                    ----------
                                                                         (COST $50,789,396)         90,856,246
                                                                                                    ----------
                         MEDICAL INSTRUMENTS AND DEVICES (2.3%)
                         -------------------------------------------------------------------------------------
                          450,000 Medtronic, Inc.                        (COST $10,483,716)         25,906,500
                                                                                                   -----------
                                                                         (COST $61,273,112)        116,762,746
                                                                                                   -----------

 16

13  STATEMENT OF INVESTMENTS DECEMBER 31, 2005 - continued
--------------------------------------------------------------------------------
    General American Investors




                        SHARES    COMMON AND PREFERRED STOCKS                                     VALUE (NOTE 1a)
-----------------------------------------------------------------------------------------------------------------
                                                                                       

MISCELLANEOUS (3.7%)              Other (b)                              (COST $42,346,406)        $42,466,400
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
OIL AND NATURAL GAS       665,000 Apache Corporation                                                45,565,800
(INCLUDING SERVICES)      758,000 Devon Energy Corporation                                          47,405,320
(29.7%)                   600,000 EOG Resources, Inc.                                               44,022,000
                          440,000 Halliburton Company                                               27,262,400
                        1,000,000 Patterson-UTI Energy, Inc.                                        32,950,000
                        1,000,000 Talisman Energy Inc.                                              52,880,000
                          330,000 Total S.A. ADR                                                    41,712,000
                        1,220,000 Weatherford International Ltd. (a)                                44,164,000
                                                                                                   -----------
                                                                        (COST $207,050,041)        335,961,520
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
RETAIL TRADE (17.9%)      700,000 Costco Wholesale Corporation                                      34,629,000
                          750,000 Dollar General Corporation                                        14,302,500
                        1,695,000 The Home Depot, Inc. (c)                                          68,613,600
                        2,500,000 The TJX Companies, Inc.                                           58,075,000
                          575,000 Wal-Mart Stores, Inc.                                             26,910,000
                                                                                                   -----------
                                                                         (COST $74,944,941)        202,530,100
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
SEMICONDUCTORS (0.5%)     323,000 Brooks Automation, Inc. (a)                                        4,047,190
                          197,000 EMCORE Corporation (a)                                             1,461,740
                                                                                                   -----------
                                                                          (COST $4,709,063)          5,508,930
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
SPECIAL HOLDING           546,000 Standard MEMS, Inc. Series A
(a)(d) (0.0%)                      Convertible Preferred                  (COST $3,003,000)                  -
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
TECHNOLOGY (2.5%)       1,900,000 Xerox Corporation (a)                  (COST $25,689,854)         27,835,000
                                                                                                   -----------
--------------------------------------------------------------------------------------------------------------
                        TOTAL COMMON AND PREFERRED STOCKS (114.9%)      (COST $714,895,565)      1,301,855,069
                                                                                                --------------
--------------------------------------------------------------------------------------------------------------

                    PRINCIPAL AMOUNT      CORPORATE NOTE
--------------------------------------------------------------------------------------------------------------
CONSUMER PRODUCTS     $35,000,000 General Motors Nova Scotia Finance Company
AND SERVICES (2.3%)                  6.85% Guaranteed Notes Due 10/15/08 (COST $33,123,366)         25,812,500
                                                                                                  ------------


                        SHARES        SHORT-TERM SECURITY AND OTHER ASSETS
--------------------------------------------------------------------------------------------------------------

                        3,822,949 SSgA Prime Money Market Fund (0.3%)     (COST $3,822,949)          3,822,949
                                                                                                    ----------

TOTAL INVESTMENTS (e) (117.5%)                                          (COST $751,841,880)      1,331,490,518
     Cash, receivables and other assets less liabilities (0.1%)                                      1,451,136
                                                                                                 -------------
                                                                                                 1,332,941,654
PREFERRED STOCK (-17.6%)                                                                          (200,000,000)
                                                                                                --------------
NET ASSETS APPLICABLE TO COMMON STOCK (100%)                                                    $1,132,941,654
                                                                                                ==============

 (a) Non-income producing security.
 (b) Securities which have been held for less than one year.
 (c) 1,000,000 shares held by custodian in a segregated custodian account as collateral for open short positions.
 (d) Restricted security acquired 12/17/99.  Fair value in the opinion of the directors.
 (e) At December 31, 2005: (1) the cost of investments for Federal income tax purposes was the same as the cost for financial
     reporting purposes, (2) aggregate gross unrealized appreciation was $602,842,012, (3) aggregate gross unrealized depreciation
     was $23,193,374, and (4) net unrealized appreciation was $579,648,638.


 17
14  NOTES TO FINANCIAL STATEMENTS
--------------------------------------------------------------------------------
    General American Investors

1. SIGNIFICANT ACCOUNTING POLICIES

General American Investors Company,  Inc. (the "Company"),  established in 1927,
is  registered  under  the  Investment  Company  Act of  1940  as a  closed-end,
diversified  management  investment  company.  It is  internally  managed by its
officers under the direction of the Board of Directors.

     The  preparation  of financial  statements  in conformity  with  accounting
principles  generally accepted in the United States requires  management to make
estimates  and  assumptions  that affect the amounts  reported in the  financial
statements  and  accompanying  notes.  Actual  results  could  differ from those
estimates.

a. SECURITY VALUATION  Securities traded on a national  securities  exchange are
valued at the last reported  sales price on the last business day of the period.
Securities  reported on the NASDAQ  national  market are valued at the  official
closing price on that day. Listed  and NASDAQ  securities for which no sales are
reported on that day and other securities traded in the over-the-counter  market
are  valued at the last bid price  (asked  price for open  short  positions  and
options written) on the valuation date.  Securities  traded primarily in foreign
markets are generally  valued at the preceding  closing price of such securities
on their  respective  exchanges  or markets.  If, after the close of the foreign
market, conditions change significantly, the price of certain foreign securities
may be adjusted  to reflect  fair value as of the time of the  valuation  of the
portfolio.  Corporate  discount  notes  are  valued  at  amortized  cost,  which
approximates market value. Investments in money market funds are valued at their
net asset value. Special holdings  (restricted  securities) and other securities
for  which  quotations  are not  readily  available  are  valued  at fair  value
determined  in good faith  pursuant to procedures  established  by and under the
general supervision of the Board of Directors.

b.  SHORT  SALES The  Company  may make  short  sales of  securities  for either
speculative or hedging purposes. When the Company makes a short sale, it borrows
the securities  sold short from a broker;  in addition,  the Company places cash
with that broker and securities in a segregated account with the custodian, both
as collateral for the short  position.  The Company may be required to pay a fee
to borrow the securities and may also be obligated to pay any dividends declared
on the  borrowed  securities.  The Company  will  realize a gain if the security
price decreases and a loss if the security price  increases  between the date of
the  short  sale  and the  date on  which  the  Company  replaces  the  borrowed
securities.

c. OPTIONS The Company may purchase and write (sell) put and call  options.  The
risk  associated  with  purchasing  an option is that the Company pays a premium
whether or not the option is exercised. Additionally, the Company bears the risk
of loss of the premium and a change in market value should the  counterparty not
perform under the contract.  Put and call options purchased are accounted for in
the same manner as portfolio securities.  Premiums received from writing options
that expire  unexercised  are treated by the Company on the  expiration  date as
realized gains from investments. The difference between the premium received and
the amount paid on effecting a closing purchase transaction, including brokerage
commissions, is also treated as a realized gain, or, if the premium is less than
the amount paid for the closing purchase  transaction,  as a realized loss. If a
call option is exercised,  the premium is added to the proceeds from the sale of
the underlying  security in determining  whether the Company has realized a gain
or loss.  If a put option is exercised,  the premium  reduces the cost basis for
the  securities  purchased  by the  Company.  The Company as writer of an option
bears the  market  risk of an  unfavorable  change in the price of the  security
underlying the written option.

d. FEDERAL INCOME TAXES The Company's  policy is to fulfill the  requirements of
the Internal  Revenue Code applicable to regulated  investment  companies and to
distribute substantially all taxable income to its stockholders. Accordingly, no
provision for Federal income taxes is required.

e. INDEMNIFICATIONS In the ordinary course of business,  the Company enters into
contracts  that contain a variety of  indemnifications.  The  Company's  maximum
exposure under these arrangements is unknown.  However,  the Company has not had
prior claims or losses pursuant to these indemnification  provisions and expects
the risk of loss thereunder to be remote.

f.  OTHER  As  customary  in  the  investment   company   industry,   securities
transactions   are  recorded  as  of  the  trade  date.   Dividend   income  and
distributions to stockholders are recorded as of the ex-dividend dates. Interest
income,  adjusted for  amortization of discount and premium on  investments,  is
earned from  settlement  date and is  recognized on the accrual  basis.  Cost of
short-term investments represents amortized cost.

--------------------------------------------------------------------------------
2.  CAPITAL STOCK AND DIVIDEND DISTRIBUTIONS

The  authorized  capital stock of the Company  consists of 50,000,000  shares of
Common Stock,  $1.00 par value, and 10,000,000 shares of Preferred Stock,  $1.00
par value, of which 29,050,399 shares and 8,000,000 shares,  respectively,  were
outstanding at December 31, 2005.

     On September 24, 2003, the Company issued and sold 8,000,000  shares of its
5.95% Cumulative  Preferred  Stock,  Series B in an underwritten  offering.  The
Preferred  Shares are noncallable for 5 years and have a liquidation  preference
of $25.00 per share plus an amount equal to accumulated and unpaid  dividends to
the date of redemption.  The underwriting discount and other expenses associated
with the Preferred  Stock  offering  amounted to $6,700,000  and were charged to
paid-in capital.

     The Company is required to allocate  distributions  from long-term  capital
gains  and other  types of income  proportionately  among  holders  of shares of
Common Stock and Preferred  Stock. To the extent that dividends on the shares of
Preferred  Stock are not paid from long-term  capital  gains,  they will be paid
from ordinary income or net short-term  capital gains or will represent a return
of capital.
 18
15  NOTES TO FINANCIAL STATEMENTS - continued
--------------------------------------------------------------------------------
    General American Investors

2.  CAPITAL STOCK AND DIVIDEND DISTRIBUTIONS -
      (Continued from previous page.)

     Under the  Investment  Company  Act of 1940,  the  Company is  required  to
maintain  an  asset  coverage  of at  least  200% for the  Preferred  Stock.  In
addition,  pursuant to the Rating Agency Guidelines,  the Company is required to
maintain a certain  discounted  asset  coverage for its portfolio that equals or
exceeds the Basic Maintenance Amount under the guidelines established by Moody's
Investors  Service,  Inc.  The  Company  has met  these  requirements  since the
issuance of the Preferred Stock. If the Company fails to meet these requirements
in the future and does not cure such  failure,  the  Company  may be required to
redeem,  in whole or in part, shares of Preferred Stock at a redemption price of
$25.00 per share plus accumulated and unpaid dividends (whether or not earned or
declared).  In  addition,  the  Company's  failure to meet the  foregoing  asset
coverage  requirements  could restrict its ability to pay dividends on shares of
Common  Stock and could lead to sales of  portfolio  securities  at  inopportune
times.

     The holders of Preferred  Stock have voting  rights  equivalent to those of
the holders of Common Stock (one vote per share) and,  generally,  vote together
with the holders of Common Stock as a single class.

     At all times,  holders  of  Preferred  Stock will elect two  members of the
Company's  Board of  Directors  and the holders of Preferred  and Common  Stock,
voting as a single  class,  will elect the remaining  directors.  If the Company
fails to pay  dividends  on the  Preferred  Stock in an amount equal to two full
years' dividends,  the holders of Preferred Stock will have the right to elect a
majority of the  directors.  In  addition,  the  Investment  Company Act of 1940
requires that approval of the holders of a majority of any outstanding Preferred
Shares, voting separately as a class, would be required to (a) adopt any plan of
reorganization  that would adversely affect the Preferred Stock and (b) take any
action  requiring a vote of security  holders,  including,  among other  things,
changes in the Company's subclassification as a closed-end investment company or
changes in its fundamental investment policies.

     The Company  classifies its Preferred Stock pursuant to the requirements of
EITF D-98,  Classification  and  Measurement  of  Redeemable  Securities,  which
requires  that  preferred  stock for  which its  redemption  is  outside  of the
company's  control should be presented outside of net assets in the statement of
assets and liabilities.

   Transactions in Common Stock during 2005 and 2004 were as follows:


                                                    SHARES                       AMOUNT
                                               ------------------------------------------------
                                               2005        2004            2005          2004
                                               ----------------          ----------------------
                                                                        
      Shares issued in payment of dividends
       (includes 1,067,491 and 508,849 shares
        issued from treasury, respectively)   1,067,491   508,849      $1,067,491      $508,849
      Increase in paid-in capital                                      35,517,225    15,273,103
                                                                       ----------    ----------
         Total increase                                                36,584,716    15,781,952
                                                                       ----------    ----------
      Shares purchased (at an average
       discount from net asset value of
       12.4% and 10.3%, respectively)        1,222,404  1,092,800      (1,222,404)   (1,092,800)
      Decrease in paid-in capital                                     (38,589,768)  (31,870,232)
                                                                      -----------   -----------
         Total decrease                                               (39,812,172)  (32,963,032)
                                                                      -----------   -----------
      Net decrease                                                    ($3,227,456) ($17,181,080)
                                                                      ===========   ===========


      At December 31, 2005, the Company held in its treasury 2,181,164 shares of Common Stock with an
      aggregate cost in the amount of $60,890,513.


Distributions for tax and book purposes are substantially the same.
As of December 31, 2005, the components of distributable earnings on a tax basis
were as follows:

  Undistributed long-term gains                     $3,969,333
  Unrealized appreciation                          579,648,638
                                                  ------------
                                                  $583,617,971
                                                  ============

To reflect  reclassification  arising from permanent "book/tax"  differences for
the year  ended  December  31,  2004  undistributed  net  investment  income was
decreased by $96,483,  undistributed  realized gain on investments was increased
by $32,883,  and  additional  paid-in  capital was  increased by $63,600.  These
differences are primarily due to  reclassification of dividends for tax purposes
and   non-deductible   expenses.   Net  assets   were  not   affected   by  this
reclassification.

To reflect  reclassification  arising from permanent "book/tax"  differences for
the year  ended  December  31,  2005  undistributed  net  investment  income was
decreased by $159,614,  undistributed realized gain on investments was increased
by $163,692,  and  additional  paid-in  capital was  decreased by $4,078.  These
differences are primarily due to  reclassification of dividends for tax purposes
and   non-deductible   expenses.   Net  assets   were  not   affected   by  this
reclassification.

--------------------------------------------------------------------------------
3.  OFFICERS' COMPENSATION
The  aggregate  compensation  paid by the  Company  during  2005 and 2004 to its
officers amounted to $5,881,000 and $4,872,000, respectively.

--------------------------------------------------------------------------------
4.  PURCHASES AND SALES OF SECURITIES
Purchases  and  sales of  securities  and  securities  sold  short  (other  than
short-term  securities  and options)  during 2005 amounted to  $254,596,163  and
$274,239,355, on long transactions,  respectively,  and $3,825,799, with respect
to short sale purchase transactions.

--------------------------------------------------------------------------------
5.  PENSION BENEFIT PLANS
The  Company  has  both a  funded  (Qualified)  and an  unfunded  (Supplemental)
noncontributory  defined benefit pension plans that cover  substantially  all of
its employees.  The plans provide defined benefits based on years of service and
final  average  salary with an offset for a portion of social  security  covered
compensation.

The Company also has funded and unfunded defined  contribution thrift plans that
cover substantially all employees. The aggregate cost of such plans for 2005 and
2004 was $815,088 and $626,307, respectively. The unfunded liability included in
other  liabilities at December 31, 2005 and 2004 was $2,598,357 and  $2,541,127,
respectively.
 19
16  NOTES TO FINANCIAL STATEMENTS - continued
--------------------------------------------------------------------------------
General American Investors

5.  PENSION BENEFIT PLANS - (Continued from previous page.)
OBLIGATIONS AND FUNDED STATUS OF DEFINED BENEFIT PLANS:



                                                          2005                               2004
                                             -------------------------------    -----------------------------------
                                             QUALIFIED  SUPPLEMENTAL            QUALIFIED  SUPPLEMENTAL
                                               PLAN         PLAN       TOTAL      PLAN        PLAN         TOTAL
                                             ---------  ------------  ------    ---------  ------------  ----------
                                                                                        
CHANGE IN BENEFIT OBLIGATION
Benefit obligation at beginning of year    $7,487,615   $2,690,636  $10,178,251 $6,793,866   $2,429,480   $9,223,346
Service cost                                  194,771      112,956      307,727    151,059       91,900      242,959
Interest cost                                 481,413      166,597      648,010    420,507      153,455      573,962
Benefits Paid                                (514,291)    (146,513)    (660,804)  (427,238)    (127,773)    (555,011)
Actuarial (gains)/losses                    1,071,753      298,925    1,370,678    395,684      144,698      540,382
Plan amendments                               180,895       16,433      197,328    153,737       (1,124)     152,613
                                            ---------    ---------   ----------  ---------    ---------   ----------
Benefit obligation at end of year           8,902,156    3,139,034   12,041,190  7,487,615    2,690,636   10,178,251
                                            ---------    ---------   ----------  ---------    ---------   ----------
CHANGE IN PLAN ASSETS
Fair value of plan assets at
    beginning of year                      14,625,572          -     14,625,572 13,029,458        -       13,029,458
Miscellaneous Adjustment                       64,946          -         64,946       -           -            -
Actual return on plan assets                1,730,760          -      1,730,760  2,023,352        -        2,023,352
Employer contributions                           -         146,513      146,513       -         127,773      127,773
Benefits paid                                (514,291)    (146,513)    (660,804)  (427,238)    (127,773)    (555,011)
                                            ---------    ---------   ----------  ---------    ---------   ----------
Fair value of plan assets at end of year   15,906,987          -     15,906,987 14,625,572        -       14,625,572
                                            ---------    ---------   ----------  ---------    ---------   ----------
FUNDED STATUS                               7,004,831   (3,139,034)   3,865,797  7,137,957   (2,690,636)   4,447,321
Unrecognized actuarial (gains)/losses         407,303      (53,983)     353,320    206,316     (352,908)    (146,592)
Unrecognized prior service cost               302,322       91,890      394,212    134,662       99,896      234,558
                                            ---------    ---------   ----------  ---------    ---------   ----------
Net amount recognized                      $7,714,456  ($3,101,127)  $4,613,329 $7,478,935  ($2,943,648)  $4,535,287
                                           ==========   ==========   ========== ==========   ==========   ==========
AMOUNTS RECOGNIZED IN THE STATEMENT OF
   ASSETS AND LIABILITIES CONSIST OF:
Prepaid benefit cost                       $7,714,456          -     $7,714,456 $7,478,935        -       $7,478,935
Accrued benefit liability                        -     ($3,101,127)  (3,101,127)     -      ($2,943,648)  (2,943,648)
                                           ----------   ----------   ---------- ----------   ----------   ----------
Net amount recognized                      $7,714,456  ($3,101,127)  $4,613,329 $7,478,935  ($2,943,648)  $4,535,287
                                           ==========   ==========   ========== ==========   ==========   ==========

Accumulated Benefit Obligation             $8,322,164   $2,725,423  $11,047,587 $6,882,288   $2,295,334   $9,177,622
Projected Benefit Obligation                8,902,156    3,139,034   12,041,190  7,487,615    2,690,636   10,178,251
Fair value of plan assets                  15,906,987          -     15,906,987 14,625,572        -       14,625,572
WEIGHTED-AVERAGE ASSUMPTIONS AS OF
   END OF FISCAL YEAR
Discount rate                                    5.50%        5.50%                   5.75%        5.75%
Expected return on plan assets                   8.75%        N/A                     8.75%        N/A
Salary scale assumption                          4.25%        4.25%                   4.25%        4.25%
COMPONENTS OF NET PERIODIC BENEFIT COST
Service cost                                 $194,771     $112,956     $307,727   $151,059      $91,900     $242,959
Interest cost                                 481,413      166,597      648,010    420,507      153,455      573,962
Expected return on plan assets             (1,077,936)         -     (1,077,936)(1,080,350)           -   (1,080,350)
Amortization of:
  Prior service cost                           13,235       24,439       37,674    (16,245)      28,565       12,320
  Recognized net actuarial loss (gain)        152,996          -        152,996        -        (24,871)     (24,871)
                                           ----------   ----------   ---------- ----------   ----------   ----------
Net periodic benefit cost                   ($235,521)    $303,992      $68,471  ($525,029)    $249,049    ($275,980)
                                           ==========   ==========   ========== ==========   ==========   ==========

WEIGHTED-AVERAGE ASSUMPTIONS FOR DETERMINING NET PERIODIC BENEFIT
   COST FOR YEARS ENDED DECEMBER 31
       Discount rate                             5.75%        5.75%                   6.25%       6.25%
       Expected long-term rate of
             return on plan assets               8.75%        N/A                     8.75%          N/A
       Rate of salary increase                   4.25%        4.25%                   4.25%        4.25%

   The Company's Pension Committee, based on input from management and an outside consultant, reviews and determines the
reasonableness of plan assumptions and the allocation of plan assets.


-------------------------------------------------------------------------------
PLAN ASSETS
The Company's qualified pension plan asset allocations
at December 31, 2005 and 2004, by asset category, are as follows:

                                December 31
                             ---------------
Asset Category               2005       2004
                             ----       ----
  Equity securities          97.3%      96.6%
  Debt securities             2.7        3.4
                            -----      -----
Total                       100.0%     100.0%
                            =====      =====


--------------------------------------------------------------------------------


CASH FLOWS                                 Qualified   Supplemental
                                              Plan         Plan         Total
                                          ----------   -------------   ---------
                                                             
Expected Company Contributions for 2006
   to Plan Participants/Total Contributions     -        $227,632      $227,632
                                          ==========   =============   =========
Estimated Future Benefit Payments:
     2006                                  $512,297      $227,632      $739,929
     2007                                   528,066       280,922       808,988
     2008                                   540,389       329,335       869,724
     2009                                   549,326       364,876       914,202
     2010                                   567,641       396,499       964,140
     2011-2015                            3,069,125     2,393,245     5,462,370


--------------------------------------------------------------------------------
6.  CALL AND PUT OPTIONS
 Transactions in written covered call and collateralized put options during the
 year ended December 31, 2005 were as follows:




                                                              Covered Calls         Collateralized Puts
                                                      --------------------------  -------------------------
                                                      Contracts         Premiums  Contracts        Premiums
                                                      ---------         --------  ---------        --------
                                                                                      
Options outstanding, December 31, 2004                    539            $90,021     500            $98,498
Options written                                         4,067          2,188,984   1,000            263,989
Options terminated in closing purchase transactions    (4,606)        (2,279,005)   (500)           (98,498)
Options exercised                                          -                 -    (1,000)          (263,989)
                                                      ---------         --------   --------        --------
Options outstanding, December 31,2005                      -                  $0       -                 $0
                                                      =========         ========   ========        ========

 20

17  NOTES TO FINANCIAL STATEMENTS - continued
--------------------------------------------------------------------------------
    General American Investors

7.  OPERATING LEASE COMMITMENT
In July 1992, the Company  entered into an operating  lease agreement for office
space  which  expires in 2007 and  provides  for future  rental  payments in the
aggregate amount of approximately  $5.6 million.  The lease agreement contains a
clause  whereby the Company  received  twenty  months of free rent  beginning in
December  1992 and  escalation  clauses  relating  to  operating  costs and real
property taxes.
     Rental expense  approximated  $298,200 for 2005. Minimum rental commitments
under the operating lease are  approximately  $505,000 per annum in 2006 through
2007.
     In January  2003,  the Company  extended a sublease  agreement  (originally
entered into in March 1996) which expires in 2007 and provides for future rental
receipts.  Minimum rental receipts under the sublease are approximately $254,000
per annum in 2006 through 2007. The Company will also receive its  proportionate
share of operating expenses and real property taxes under the sublease.

--------------------------------------------------------------------------------
8.  SUBSEQUENT EVENT
On January 18,  2006,  the Board of  Directors  declared  on the Common  Stock a
distribution  of  $0.138  per  share  from net  long-term  capital  gains.  This
distribution is payable in cash on February 13, 2006.
--------------------------------------------------------------------------------


FINANCIAL HIGHLIGHTS
--------------------------------------------------------------------------------
General American Investors

"The  following  table  shows  per  share  operating   performance  data,  total
investment  return,  ratios and supplemental data for each year in the five-year
period  ended  December  31,  2005.  This  information  has  been  derived  from
information  contained in the financial statements and market price data for the
Company's shares."





                                                       2005        2004          2003          2002          2001
                                                     --------    --------      --------      --------      --------
                                                                                          
   PER SHARE OPERATING PERFORMANCE
     Net asset value, beginning of year                $35.49      $33.11        $26.48        $35.14        $39.91
                                                     --------    --------      --------      --------      --------
        Net investment income                             .19         .32           .03           .19           .41
        Net gain (loss) on securities - realized
          and unrealized                                 5.85        3.48          7.72         (7.88)         (.66)
                                                     --------    --------      --------      --------      --------
        Distributions on Preferred Stock:
          Dividends from net investment income           (.03)       (.09)         (.01)         (.12)         (.03)
          Distributions from net short-term
            capital gains                                (.08)         -             -             -           (.04)
          Distributions from net long-term
            capital gains                                (.30)       (.32)         (.35)         (.23)         (.29)
                                                     --------    --------      --------      --------      --------
                                                         (.41)       (.41)         (.36)         (.35)         (.36)
                                                     --------    --------      --------      --------      --------
          Total from investment operations               5.63        3.39          7.39         (8.04)         (.61)
                                                     --------    --------      --------      --------      --------
     Less distributions on Common Stock:
          Dividends from investment income               (.15)       (.23)         (.02)         (.02)         (.37)
          Distributions from net short-term
            capital gains                                (.44)         -             -           (.19)         (.51)
          Distributions from net long-term
            capital gains                               (1.53)       (.78)         (.52)         (.41)        (3.28)
                                                     --------    --------      --------      --------      --------
                                                        (2.12)      (1.01)         (.54)         (.62)        (4.16)
                                                     --------    --------      --------      --------      --------

     Capital Stock transaction -
         effect of Preferred Stock offering               -            -           (.22)           -             -
                                                     --------    --------      --------      --------      --------
     Net asset value, end of year                      $39.00      $35.49        $33.11        $26.48        $35.14
                                                     ========    ========      ========      ========      ========
     Per share market value, end of year               $34.54      $31.32        $29.73        $23.85        $33.47
                                                     ========    ========      ========      ========      ========

   TOTAL INVESTMENT RETURN - Stockholder
     Return, based on market price per share            17.40%       8.79%        27.01%       (27.21)%        4.33%

   RATIOS AND SUPPLEMENTAL DATA
     Net assets applicable to Common Stock,
        end of year (000's omitted)                $1,132,942  $1,036,393      $986,335      $809,192    $1,097,530
     Ratio of expenses to average net assets
        applicable to Common Stock                       1.25%       1.15%         1.23%         0.92%         0.97%
     Ratio of net income to average net assets
        applicable to Common Stock                       0.51%       0.94%         0.13%         0.61%         1.15%
     Portfolio turnover rate                            20.41%      16.71%        18.62%        22.67%        23.81%

   PREFERRED STOCK
     Liquidation value, end of year
        (000's omitted)                              $200,000    $200,000      $200,000      $150,000      $150,000
     Asset coverage                                       666%        618%          593%          639%          832%
     Liquidation preference per share                  $25.00      $25.00        $25.00        $25.00        $25.00
     Market value per share                            $24.07      $24.97        $25.04        $25.85        $25.90


 21
18  REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
--------------------------------------------------------------------------------
    General American Investors

TO THE  BOARD OF  DIRECTORS  AND  STOCKHOLDERS  OF  GENERAL  AMERICAN  INVESTORS
COMPANY, INC.

We have audited the accompanying statement of assets and liabilities,  including
the statements of investments, of General American Investors Company, Inc. as of
December 31, 2005,  and the related  statements of operations and changes in net
assets  for each of the two  years  in the  period  then  ended,  and  financial
highlights for each of the five years in the period then ended.  These financial
statements and financial  highlights  are the  responsibility  of the Company's
management. Our responsibility is to express an opinion on these financial
statements and financial highlights based on our audits.

We conducted our audits in accordance  with the standards of the Public  Company
Accounting Oversight Board (United States). Those standards require that we plan
and perform the audit to obtain reasonable assurance about whether the financial
statements and financial highlights are free of material  misstatement.  We were
not engaged to perform an audit of the Company's internal control over financial
reporting.  Our audits included consideration of internal control over financial
reporting as a basis for designing audit  procedures that are appropriate in the
circumstances,  but  not  for  the  purpose  of  expressing  an  opinion  on the
effectiveness  of the  Company's  internal  control  over  financial  reporting.
Accordingly,  we express no such opinion. An audit includes examining, on a test
basis, evidence supporting amounts and disclosures in the financial statements.
Our  procedures  included  confirmation  of securities  owned as of December 31,
2005, by correspondence with the custodian and brokers.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,   as  well  as  evaluating  the  overall  financial  statement  pre-
sentation.  We  believe  that our  audits  provide  a  reasonable  basis for our
opinion.

In our opinion,  the financial  statements and financial  highlights referred to
above  present  fairly,  in all material  respects,  the  financial  position of
General American  Investors  Company,  Inc. at December 31, 2005, the results of
its  operations  and the  changes in its net assets for each of the two years in
the period then ended,  and the financial  highlights for each of the five years
in the period then ended, in conformity with U.S. generally accepted  accounting
principles.

Ernst & Young

New York, New York
January 18, 2006
 22
19  OFFICERS
--------------------------------------------------------------------------------
    General American Investors



   NAME (AGE)                 PRINCIPAL OCCUPATION             NAME (AGE)                PRINCIPAL OCCUPATION
    EMPLOYEE SINCE              DURING PAST 5 YEARS             EMPLOYEE SINCE            DURING PAST 5 YEARS
-----------------------------------------------------------------------------------------------------------------------------------
                                                                                 

Spencer Davidson (63)         President and Chief               Sally A. Lynch, Ph.D.(46) Vice-President of the Company
     1994                     Executive Officer of the              1997                  since 2006
                              Company since 1995                                          securities analyst
                                                                                          (biotechnology industry)

Andrew V. Vindigni (46)       Vice-President of the             Peter P. Donnelly (57)    Vice-President of the
     1988                     Company since 1995                    1974                  Company since 1991
                              securities analyst (financial                               securities trader
                              services industry)
                                                                Diane G. Radosti (53)     Treasurer of the
                                                                    1980                  Company since 1990
Eugene S. Stark (47)          Vice-President, Administration                              Principal Accounting
     2005                     of the Company since 2005                                   Officer since 2003
                              Principal Financial Officer
                              since 2005; Chief Compliance      Carole Anne Clementi (59) Secretary of the Company
                              Officer since 2006;                   1982                  since 1994
                              Chief Financial Officer of                                  shareholder relations
                              Prospect Energy Corporation                                 and office management
                              (2005);
                              Vice-President of
                              Prudential Financial, Inc.        Craig A. Grassi (37)      Assistant Vice-President of
                              (1987-2004)                           1991                  the Company since 2005;
                                                                                          employee since 1991
Jesse Stuart (39)             Vice-President of the Company                               information technology
     2003                     since 2006
                              securities analyst (general       Maureen E. LoBello (55)   Assistant Secretary of the
                              industries);                          1992                  Company since 2005;
                              securities analyst &portfolio                               employee since 1992
                              manager of Scudder, Stevens                                 benefits administration
                              and Clark (1996-2003)



All  officers  serve  for a term of one year  and are  elected  by the  Board of
Directors at the time of its annual organization meeting on the second Wednesday
in  April.  The  address  for  each  officer  is  the  Company's  office.  Other
directorships  and  affiliations  for Mr.  Davidson  are shown in the listing of
Directors on page 20.

SERVICE ORGANIZATIONS
--------------------------------------------------------------------------------
COUNSEL
Sullivan & Cromwell LLP

INDEPENDENT AUDITORS
Ernst & Young LLP

CUSTODIAN
State Street Bank and Trust Company

TRANSFER AGENT AND REGISTRAR
American Stock Transfer & Trust Company
59 Maiden Lane
New York, NY 10038
1-800-413-5499
www.amstock.com

--------------------------------------------------------------------------------

In addition to purchases of the  Company's  Common Stock as set forth in Note 2,
on page 15, purchases of Common Stock may be made at such times, at such prices,
in such amounts and in such manner as the Board of Directors may deem advisable.

In addition to distributing  financial statements as of the end of each quarter,
General  American  Investors  files a Quarterly  Schedule of Portfolio  Holdings
(Form N-Q) with the  Securities and Exchange  Commission  (SEC) as of the end of
the first and third calendar quarters.  The Company's Forms N-Q are available at
www.generalamericaninvestors.com  and on the SEC's website:  www.sec.gov.  Also,
Forms N-Q may be  reviewed  and  copied at the SEC's  Public  Reference  Room in
Washington,  DC. Information on the operation of the SEC's Public Reference Room
may be obtained by calling 1-800-SEC-0330.  A copy of the Company's Form N-Q may
be obtained by calling us at 1-800-436-8401.

On May 6, 2005, the Company submitted a CEO annual certification to the New York
Stock  Exchange  ("NYSE") on which the  Company's  principal  executive  officer
certified  that he was not  aware,  as of that  date,  of any  violation  by the
Company of the NYSE's Corporate  Governance listing standards.  In addition,  as
required by Section 302 of the Sarbanes-Oxley Act of 2002 and related SEC rules,
the Company's principal executive and principal financial officer made quarterly
certifications, included in filings with the SEC on Forms N-CSR and N-Q relating
to, among other things,  the Company's  disclosure  controls and  procedures and
internal control over financial reporting, as applicable.
 23

20  DIRECTORS
--------------------------------------------------------------------------------
    General American Investors




   NAME (AGE)                     PRINCIPAL OCCUPATION
   DIRECTOR SINCE                 DURING PAST 5 YEARS                   OTHER DIRECTORSHIPS AND  AFFILIATIONS
---------------------------------------------------------------------------------------------------------------------------------
   INDEPENDENT ("DISINTERESTED") DIRECTORS
---------------------------------------------------------------------------------------------------------------------------------
                                                                  
   Lawrence B. Buttenwieser (74)  Counsel 2002-present
   Chairman of the                Partner 1966-2002
     Board of Directors           Katten Muchin Zavis Rosenman
   1967                           and predecessor firms (lawyers)

   Arthur G. Altschul, Jr. (41)   Managing Member                       Delta Opportunity Fund, Ltd., Director
   1995                           Diaz & Altschul Capital               Medicis Pharmaceutical Corporation, Director
                                    Management, LLC                     Medrium, Inc., Chairman, Board of Directors
                                  (private investment company)          National Public Radio Foundation, Trustee
                                                                        Neurosciences Research Foundation, Trustee

   Lewis B. Cullman (87)          Managing Member                       Chess-in-the-Schools, Chairman, Board of Trustees
   1961                           Cullman Ventures LLC                  Metropolitan Museum of Art, Honorary Trustee
                                                                        Museum of Modern Art, Vice Chairman,
                                                                          International Council and Honorary Trustee
                                                                        Neurosciences Research Foundation, Vice Chairman,
                                                                          Board of Trustees
                                                                        The New York Botanical Garden, Senior Vice
                                                                          Chairman, Board of Managers

   Gerald M. Edelman (76)         Member, Professor and Chairman of     Neurosciences Institute of the Neurosciences
   1976                              the Department of Neurobiology       Research Foundation,  Director and President
                                  The Scripps Research Institute

   John D. Gordan, III (60)       Partner
   1986                           Morgan, Lewis & Bockius LLP
                                  (lawyers)

   Sidney R. Knafel (75)          Managing Partner                      IGENE Biotechnology, Inc., Director
   1994                           SRK Management Company                Insight Communications Company, Inc.,
                                  (private investment company)            Chairman, Board of Directors
                                                                        VirtualScopics, Inc., Director
                                                                        Vocollect, Inc., Director

   Richard R. Pivirotto (75)      President                             Associated Community Bancorp, Inc., Director
   1971                           Richard R. Pivirotto Co., Inc.        General Theological Seminary, Trustee
                                  (self-employed consultant)            Greenwich Hospital Corporation, Trustee
                                                                        Immunomedics, Inc., Director
                                                                        Princeton University, Charter Trustee Emeritus

   D. Ellen Shuman (50)           Vice President and                    Bowdoin College, Trustee
   2004                             Chief Investment Officer            Edna McConnell Clark Foundation,
                                  Carnegie Corporation of New York        Investment Advisor
                                                                        The Investment Fund for Foundations, Director
                                                                        Meristar Hospitality Corporation, Director

   Joseph T. Stewart, Jr. (76)    Corporate director and trustee        Foundation of the University of
   1987                           Executive Consultant                    Medicine and Dentistry of New Jersey, Trustee
                                  Johnson & Johnson (1990-1999)         Marine Biological Laboratory, Member,
                                                                          Advisory Council
                                                                        United States Merchant Marine Academy, Trustee,
                                                                          Board of Advisors
                                                                        United States Merchant Marine Academy Foundation,
                                                                          Trustee

   Raymond S. Troubh (79)         Financial Consultant                  Diamond Offshore Drilling, Inc., Director
   1989                                                                 Gentiva Health Services, Inc., Director
                                                                        Petrie Stores Liquidating Trust, Trustee
                                                                        Portland General Electric Company, Director
                                                                        Triarc Companies, Inc., Director

   INSIDE ("INTERESTED") DIRECTOR
------------------------------------------------------------------------------------------------------------------------------------
   Spencer Davidson (63)          President and Chief Executive Officer Medicis Pharmaceutical Corporation, Director
   1995                           General American Investors            Neurosciences Research Foundation, Trustee
                                    Company, Inc. since 1995

All Directors  serve for a term of one year and are elected by  Stockholders  at
the time of the annual meeting on the second Wednesday in April. The address for
each Director is the Company's office.

------------------------------------------------------------------------------------------------------------------------------------
                                               William T. Golden, Director Emeritus


 24
                    General American Investors Company, Inc.
                    450 Lexington Avenue, New York, NY 10017
                         (212) 916-8400 (800) 436-8401
                       E-mail:InvestorRelations@gainv.com
                        www.generalamericaninvestors.com

 25
ITEM 2. CODE OF ETHICS.

On July 9, 2003, the Board of Directors adopted a code of ethics that applies to
registrant's  principal  executive and senior  financial  officers.  The code of
ethics    is    available     on     registrant's     Internet     website    at
http://www.generalamericaninvestors.com/corporateinfo.html. Since the code of
ethics was adopted there have been no amendments to the code nor have there been
granted any waivers from any provisions of the code of ethics.

ITEM 3. AUDIT COMMITTEE FINANCIAL EXPERT.

The board of directors has determined  that none of the members of  registrant's
audit committee meets the definition of "audit  committee  financial  expert" as
the term has been defined by the U.S.  Securities and Exchange  Commission  (the
"Commission").  In addition,  the board of  directors  has  determined  that the
members  of  the  audit  committee  have  sufficient   financial  expertise  and
experience to perform the duties and responsibilities of the audit committee.

ITEM 4. PRINCIPAL ACCOUNTANT FEES AND SERVICES.

(a)  AUDIT FEES  The aggregate  fees paid and  accrued  by the  registrant  for
professional services rendered by its independent  auditors,  Ernst & Young LLP,
for the audit of the registrant's annual financial  statements and the review of
the registrant's semi-annual financial statements for 2005 and 2004 were $75,000
and $69,600, respectively.

(b) AUDIT RELATED FEES The aggregate  fees paid or accrued by the registrant for
audit-related  professional  services rendered by Ernst & Young LLP for 2005 and
2004 were $23,700 and $20,500, respectively.  Such services and related fees for
2005 and 2004 included:  performance of agreed upon  procedures  relating to the
preferred stock basic  maintenance  reports  ($6,000 and $5,000,  respectively),
review of  quarterly  employee  security  transactions  and  issuance  of report
thereon ($14,000 and $12,000,  respectively)  and other  audit-related  services
($3,700 and $3,500, respectively).

(c)  TAX  FEES  The  aggregate  fees  paid  or  accrued  by the  registrant  for
professional  services  rendered  by  Ernst & Young  LLP for the  review  of the
registrant's  federal,  state  and  city  income  tax  returns  and  excise  tax
calculations for 2005 and 2004 were $13,000 and $12,500, respectively.

(d)  ALL OTHER FEES  No such fees were billed to the registrant by Ernst & Young
LLP for 2005 or 2004.

(e)(1) AUDIT COMMITTEE PRE-APPROVAL POLICY All services to be performed for the
registrant by Ernst & Young LLP must be pre-approved by the audit committee. All
services performed during 2005 and 2004 were pre-approved by the committee.

   (2) Not applicable.

(f) Not applicable.

(g)  The  aggregate  fees  paid  or  accrued  by the  registrant  for  non-audit
professional  services  rendered by Ernst & Young LLP to the registrant for 2005
and 2004 were $36,700 and $33,000, respectively.

(h) Not applicable.

ITEM 5. AUDIT COMMITTEE OF LISTED REGISTRANTS.

(a)  The  registrant  has  a  separately-designated   standing  audit  committee
established in accordance  with Section  3(a)(58)(A) of the Securities  Exchange
Act of 1934. The members of the audit committee are: Sidney R. Knafel, chairman,
Arthur G. Altschul, Jr., Lawrence B. Buttenwieser, Lewis B. Cullman and John D.
Gordan, III.

(b) Not applicable.

ITEM 6. SCHEDULE OF INVESTMENTS

The schedule of investments in securities of unaffiliated issuers is included as
part of the report to stockholders filed under Item 1 of this form.

ITEM 7. DISCLOSURE OF PROXY VOTING POLICIES AND PROCEDURES FOR CLOSED-END
MANAGEMENT INVESTMENT COMPANIES.

                    General American Investors Company, Inc.

                      PROXY VOTING POLICIES AND PROCEDURES


     General  American  Investors  Company,  Inc.  (the  "Company")  is uniquely
structured as an internally managed closed-end  investment company. Our research
efforts,  including the receipt and analysis of proxy  material,  are focused on
the securities in the Company's  portfolio,  as well as  alternative  investment
opportunities.  We vote proxies relating to our portfolio securities in the best
long-term interests of the Company.

     Our investment  approach  stresses  fundamental  security  analysis,  which
includes  an  evaluation  of the  integrity,  as  well as the  effectiveness  of
management  personnel.  In proxy material,  we review  management  proposals and
management  recommendations relating to shareholder proposals in order to, among
other things, gain assurance that management's positions are consistent with its
integrity and the long-term  interests of the company. We generally find this to
be the case and, accordingly, give significant weight to the views of management
when we vote proxies.

     Proposals  that may have an  impact  on the  rights  or  privileges  of the
securities held by the Company would be reviewed very carefully. The explanation
for a negative impact could justify the proposal; however, if such justification
were not present, we would vote against a significant reduction in the rights or
privileges associated with any of our holdings.

Proposals   relating  to  corporate   governance   matters  are  reviewed  on  a
case-by-case  basis.  When they involve  changes in the state of  incorporation,
mergers or other restructuring,  we would, if necessary,  complete our review of
the rationale for the proposal by contacting company  representatives  and, with
few  exceptions,  vote  in  favor  of  management's  recommendations.  Proposals
relating to anti-takeover provisions, such as staggered boards, poison pills and
supermajorities could be more problematic.  They would be considered in light of
our  assessment  of the  capability of current  management,  the duration of the
proposal, the negative impact it might have on the attractiveness of the company
to future "investors," among other factors. We can envision  circumstances under
which we would vote against an anti-takeover provision.

     Generally,  we would vote with management on proposals  relating to changes
to the company's capital structure, including increases and decreases of capital
and  issuances  of  preferred  stock;  however,  we would  review  the facts and
circumstances associated with each proposal before finalizing our decision.

     Well-structured stock option plans and management compensation programs are
essential for companies to attract and retain high caliber management personnel.
We generally vote in favor of proposals relating to these issues; however, there
could be an occasion on which we viewed such a proposal as over  reaching on the
part of management or having the potential for excessive  dilution when we would
vote against the proposal.

     Corporations should act in a responsible manner toward their employees, the
communities in which they are located, the customers they serve and the world at
large.  We have  observed  that most  stockholder  proposals  relating to social
issues focus on a narrow issue and the corporate position set forth in the proxy
material  provides a well-considered  response  demonstrating an appropriate and
responsible  action or position.  Accordingly,  we generally support  management
recommendations  on these types of proposals;  however,  we would  consider each
proposal on a case-by-case basis.

     We take voting proxies of securities  held in our portfolio very seriously.
As indicated above, it is an integral part of the analytical  process at General
American  Investors.  Each  proposal and any  competing  interests  are reviewed
carefully on a case-by-case basis.  Generally, we support and vote in accordance
with the  recommendations of management;  however,  the overriding basis for the
votes we cast is the best long-term interests of the Company.

Date: July 9, 2003

Item 8. PORTFOLIO MANAGERS OF CLOSED-END MANAGEMENT INVESTMENT COMPANIES.

Mr.  Spencer  Davidson,  President and Chief  Executive  Officer,  serves as the
Portfolio  Manager  of the  registrant  and is  responsible  for its  day-to-day
management.  He has served in this capacity  since 1995.  Mr.  Davidson does not
provide such  services for any other  registered  investment  companies,  pooled
investment vehicles,  or other accounts.  For performing such  responsibilities,
Mr.  Davidson  receives cash  compensation  in the form of a fixed salary and an
annual performance bonus. The annual performance bonus is principally based upon
the absolute  performance of the  registrant  and its relative  performance to a
closed-end  management  investment  company peer group (comprised of core equity
funds)  and the S&P 500 Index.  Performance  is  evaluated  in  December  by the
Compensation  Committee  of the board of  directors  (the  members  of which are
independent  and  consult  with the full  board of  directors),  based  upon the
registrant's  net asset  value  return and total  investment  return  during the
twelve months ended October 31. Additional consideration is given to performance
during  the  subsequent  intervening  period  and to  market  compensation  data
provided  by  a  noted  industry  compensation  consulting  firm.  Mr.  Davidson
beneficially owns in excess of $1 million of the registrant's outstanding equity
securities.



ITEM 9. PURCHASES OF EQUITY SECURITIES BY CLOSED-END MANAGEMENT INVESTMENT
COMPANY AND AFFILIATED PURCHASERS.



                                                   REGISTRANT PURCHASES OF EQUITY SECURITIES

                                                               (c) Total Number of Shares      (d) Maximum Number (or Approximate
  Period         (a) Total Number         (b) Average Price    (or Units) Purchased as Part     Dollar Value) of Shares (or Units)
                     of Shares               Paid per Share       of Publicly Announced         that May Yet Be Purchased Under
   2005         (or Units) Purchased            (or Unit)           Plans or Programs               the Plans or Programs
------------------------------------------------------------------------------------------------------------------------------------
                                                                                     
07/01-07/31            97700                  33.5250               97700                        492400

08/01-08/31           105400                  34.4012              105400                        387000

09/01-09/30            69000                  34.6016               69000                        318000

10/01-10/31            82300                  33.8024               82300                        235700

11/01-11/30            87100                  34.2758               87100                        148600

12/01-12/31           144700                  34.9293              144700                        753900
                     -------                 --------             -------                        ------
Total                 586200                                       586200
                     =======                                      =======

        Note - On July 13, 2005 and December 14, 2005, the Board of Directors authorized and the registrant announced the repurchase
               of up to 500,000 and 750,000 shares, respectively, of the registrant's common stock when the shares are trading at
               a discount from the underlying net asset value of at least 8%. This represents a continuation of a repurchase program
               which began in March 1995.  As of the beginning of the period, July 1, 2005, there were 90,100 shares available for
               repurchase under such authorization.  As of the end of the period, December 31, 2005, there were 753,900
               shares available for repurchase under this program.





ITEM 10.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS.

There have been no material changes to the procedures by which  shareholders may
recommmend  nominees to the registrant's  board of directors as set forth in the
registrant's Proxy Statement, dated February 28, 2005.

ITEM 11. CONTROLS AND PROCEDURES.


Conclusions of principal officers concerning controls and procedures

(a) As of December 30, 2005, an evaluation was performed  under the  supervision
and with  the  participation  of the  officers  of  General  American  Investors
Company,  Inc. (the  "Registrant"),  including the principal  executive  officer
("PEO") and principal  financial officer ("PFO"), to assess the effectiveness of
the Registrant's  disclosure controls and procedures.  Based on that evaluation,
the  Registrant's  officers,  including the PEO and PFO,  concluded  that, as of
December 30, 2005, the  Registrant's  disclosure  controls and  procedures  were
reasonably  designed  so as to  ensure:  (1)  that  information  required  to be
disclosed  by the  Registrant  on  Form  N-CSR  and  on  Form  N-Q is  recorded,
processed,  summarized  and reported  within the time  periods  specified by the
rules and forms of the Securities and Exchange Commission; and (2) that material
information  relating  to the  Registrant  is made  known  to the PEO and PFO as
appropriate to allow timely decisions regarding required disclosure.

(b) There have been no significant changes in the Registrant's  internal control
over  financial  reporting  (as defined in Rule  30a-3(d)  under the  Investment
Company Act of 1940 (17 CFR 270.30a-3(d))  that occurred during the Registrant's
last fiscal quarter that has  materially  affected,  or is reasonably  likely to
materially affect, the Registrant's internal control over financial reporting.

ITEM 12. EXHIBITS

(a)(1) As indicated in Item 2., the code of ethics is posted on the registrant's
       Internet website.

(a)(2) The certifications of the principal executive officer and the principal
       financial officer pursuant to Rule 30a-2(a)under the Investment Company
       Act of 1940 are attached hereto as Exhibit 99 CERT.

(a)(3) There were no written  solicitations  to  purchase  securities under
       the Rule 23c-1  under the  Investment Company Act of 1940 during the
       period covered by the report.

(b)    The certifications of the principal executive officer and the principal
       financial officer pursuant to Rule 30a-2(b) under the Investment Company
       Act of 1940 are attached hereto as Exhibit 99.906 CERT.


 27
SIGNATURES

  Pursuant to the requirements of the Securities Exchange Act of 1934 and
the Investment Company Act of 1940, the registrant has duly caused this report
to be signed on its behalf by the undersigned, thereunto duly authorized.

General American Investors Company, Inc.

By: /s/Eugene S. Stark
    Eugene S. Stark
    Vice-President, Administration

Date: February 9, 2006

  Pursuant to the requirements of the Securities Exchange Act of 1934 and
the Investment Company Act of 1940, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on the
dates indicated.

By: /s/Spencer Davidson
    Spencer Davidson
    President and Chief Executive Officer
    (Principal Executive Officer)

Date: February 9, 2006

By: /s/Eugene S. Stark
    Eugene S. Stark
    Vice-President, Administration
    (Principal Financial Officer)

Date: February 9, 2006