UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940 |
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. | SEC 1473 (7-02) | ||
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. |
1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security | 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
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Date Exercisable | Expiration Date | Title | Amount or Number of Shares |
Reporting Owner Name / Address | Relationships | |||
Director | 10% Owner | Officer | Other | |
OXFORD BIOSCIENCE PARTNERS IV LP 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
MRNA FUND II LP 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
OBP MANAGEMENT IV LP 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
BARNES JEFFREY T 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
CARTHY MARK 222 BERKELEY ST. BOSTON, MA 02116 |
 X |  X |  |  |
FLEMING JONATHAN 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
LYTTON MICHAEL 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
WALTON ALAN G 222 BERKELEY ST. BOSTON, MA 02116 |
 |  X |  |  |
/s/ Jonathan J. Fleming, as general partner of the general partner of Oxford Bioscience Partners IV L.P. | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Jonathan J. Fleming, as general partner of the general partner of mRNA Fund II L.P. | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Jonathan J. Fleming, as general partner of OBP Management IV L.P. | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Raymond Charest, as attorney-in-fact for Jeffrey T. Barnes | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Mark P. Carthy | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Jonathan J. Fleming | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Michael E. Lytton | 03/14/2005 | |
**Signature of Reporting Person | Date | |
/s/ Alan G. Walton | 03/14/2005 | |
**Signature of Reporting Person | Date |
* | If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** | Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) | Securities held of record by Oxford Bioscience Partners IV L.P. ("Oxford IV"). By virtue of their relationship as affiliated limited partnerships, whose sole general partner shares individual general partners, Oxford IV and mRNA Fund II L.P. ("mRNA") may be deemed to share voting power and the power to direct the disposition of the shares which each partnership owns of record. OBP Management IV L.P. ("OBP IV") (as the general partner of Oxford IV and mRNA II), may also be deemed to own beneficially the shares held of record by Oxford IV and mRNA II. Each of Messrs. Barnes, Carthy (who is a Director of the issuer), Fleming, Lytton, and Walton, the individual general partners of OBP IV, may be deemed to own beneficially the shares held by Oxford IV and mRNA II. |
(2) | Securities held of record by mRNA. By virtue of their relationship as affiliated limited partnerships, whose sole general partner shares individual general partners, Oxford IV and mRNA may be deemed to share voting power and the power to direct the disposition of the shares which each partnership owns of record. OBP IV (as the general partner of Oxford IV and mRNA II), may also be deemed to own beneficially the shares held of record by Oxford IV and mRNA II. Each of Messrs. Barnes, Carthy (who is a Director of the issuer), Fleming, Lytton, and Walton, the individual general partners of OBP IV, may be deemed to own beneficially the shares held by Oxford IV and mRNA II. |