SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D
                    Under the Securities Exchange Act of 1934

                               (Amendment No. 20)*

                            ISCO International, Inc.
                                (Name of Issuer)

                          Common Stock, par value $.001
                         (Title of Class of Securities)

                                    46426P103
                                 (CUSIP Number)

                            Stephen M. Schultz, Esq.
           Kleinberg, Kaplan, Wolff & Cohen, P.C., 551 Fifth Avenue
                            New York, New York 10176
                               Tel: (212) 986-6000
(Name, Address and Telephone Number of Person Authorized to Receive Notices and
                                Communications)

                                January 10, 2005
             (Date of Event which Requires Filing of this Statement)

     If the filing  person has  previously  filed a statement on Schedule 13G to
report the acquisition  which is the subject of this Schedule 13D, and is filing
this  schedule  because  of Rule  13d-1(e),  13d-1(f)  or  13d-1(g),  check  the
following box [ ].

Note:  Schedules  filed in paper format shall include a signed original and five
copies of the  schedule,  including  all  exhibits.  See Rule 13d-7(b) for other
parties to whom copies are to be sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

     The  information  required on the remainder of this cover page shall not be
deemed to be "filed"  for the purpose of Section 18 of the  Securities  Exchange
Act of 1934 ("Act") or otherwise  subject to the  liabilities of that section of
the Act but shall be subject to all other  provisions of the Act  (however,  see
the Notes).




1.       NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
                  Elliott Associates, L.P.

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
         (a)[x]
         (b)[ ]

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*
                  WC

5.       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
         ITEMS 2(d) or 2(e) [  ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION
                  Delaware

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH

7.       SOLE VOTING POWER
                  16,379,788

8        SHARED VOTING POWER
                  0

9.       SOLE DISPOSITIVE POWER
                  16,379,788

10.      SHARED DISPOSITIVE POWER
                  0

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
                  16,379,788

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
         EXCLUDES CERTAIN SHARES*   [ ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
                  10.2%

14.      TYPE OF REPORTING PERSON*
                  PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!



1.       NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
                  Elliott International, L.P.

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
         (a)[x]
         (b)[ ]

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*
                  WC

5.       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
         REQUIRED PURSUANT TO ITEMS 2(d) or 2(e)     [  ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION
                  Cayman Islands, British West Indies

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH

7.       SOLE VOTING POWER
                  0

8.       SHARED VOTING POWER
                  11,914,339

9.       SOLE DISPOSITIVE POWER
                  0

10.      SHARED DISPOSITIVE POWER
                  11,914,339

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
         REPORTING PERSON
                  11,914,339

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
         EXCLUDES CERTAIN SHARES*           [ ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
                  7.4%

14.      TYPE OF REPORTING PERSON*
                  PN

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!



1.       NAME OF REPORTING PERSONS
         I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
                  Elliott International Capital Advisors, Inc.

2.       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
         (a)[x]
         (b)[ ]

3.       SEC USE ONLY

4.       SOURCE OF FUNDS*
                  00

5.       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO
         ITEMS 2(d) or 2(e) [  ]

6.       CITIZENSHIP OR PLACE OF ORGANIZATION
                  Delaware

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH
REPORTING PERSON WITH

7.       SOLE VOTING POWER
                  0

8.       SHARED VOTING POWER
                  11,914,339

9.       SOLE DISPOSITIVE POWER
                  0

10.      SHARED DISPOSITIVE POWER
                  11,914,339

11.      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
         REPORTING PERSON
                  11,914,339

12.      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11)
         EXCLUDES CERTAIN SHARES*           [ ]

13.      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
                  7.4%

14.      TYPE OF REPORTING PERSON*
                  CO

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!



     This  statement is filed with respect to the shares of common stock,  $.001
par value  (the  "Common  Stock") of ISCO  International,  Inc.  (the  "Issuer")
beneficially owned by Elliott Associates, L.P. and its wholly-owned subsidiaries
(collectively, "Elliott"), Elliott International, L.P. ("Elliott International")
and Elliott  International  Capital Advisors,  Inc.  ("EICA")(collectively,  the
"Reporting  Persons")  as of January  19,  2005 and amends and  supplements  the
Schedule 13D dated April 7, 1999, as previously  amended (the  "Schedule  13D").
Except  as set forth  herein,  the  Schedule  13D,  as  previously  amended,  is
unmodified.

ITEM 3.         Source and Amount of Funds or Other Consideration

     The source and amount of funds used by Elliott in making its  purchases  of
the shares of Common Stock beneficially owned by it are set forth below:

SOURCE OF FUNDS                                      AMOUNT OF FUNDS
Working Capital                                      $5,227,908

     The source and amount of funds used by Elliott  International in making its
purchases of the shares of Common Stock  beneficially  owned by it are set forth
below:

SOURCE OF FUNDS                                      AMOUNT OF FUNDS
Working Capital                                      $8,246,115

ITEM 5.         Interest in Securities of the Issuer.

     (a) Elliott  beneficially  owns an aggregate of 16,379,788 shares of Common
Stock, constituting 10.2% of all of the outstanding shares of Common Stock.

     Together,  Elliott  International and EICA beneficially own an aggregate of
11,914,339  shares of Common Stock,  constituting 7.4% of all of the outstanding
shares of Common Stock.

     Elliott, Elliott International and EICA's aggregate beneficial ownership of
Common  Stock  equals  28,294,127  shares,   comprising  17.6%  of  all  of  the
outstanding shares of Common Stock.

     (b)  Elliott has the power to vote or direct the vote of, and to dispose or
direct the disposition of, the shares of Common Stock beneficially owned by it.

     Elliott  International has the shared power with EICA to vote or direct the
vote of, and to dispose or direct the disposition of, the shares of Common Stock
owned  by  Elliott   International.   Information   regarding  each  of  Elliott
International  and  EICA is set  forth  in Item 2 of  this  Schedule  13D and is
expressly incorporated herein by reference herein.



     (c) The following  transactions  were  effected by Elliott  during the past
sixty (60) days:

                                               Approx. Price per
                              Amount of Shs.   Share (excl. of
Date              Security    Bought (Sold)    commissions)
----              --------    --------------   -----------------

1/10/05           Common        (390,000)           $0.48

     The following  transactions were effected by Elliott  International  during
the past sixty (60) days:

                                               Approx. Price per
                              Amount of Shs.   Share (excl. of
Date              Security    Bought (Sold)    commissions)
----              --------    --------------   -----------------

1/10/05           Common        (585,300)           $0.48

     All of the above transactions were effected on the American Stock Exchange.

     No other transactions with respect to the Common Stock that are required to
be reported and have not been previously  reported on Schedule 13D were effected
by any of the Reporting Persons during the past sixty (60) days.

     (d) No person  other than  Elliott has the right to receive or the power to
direct the receipt of  dividends  from,  or the  proceeds  from the sale of, the
shares of Common Stock beneficially owned by Elliott.

     No  person  other  than  Elliott  International  and EICA has the  right to
receive or the power to direct the receipt of  dividends  from,  or the proceeds
from the sale of,  the  shares of Common  Stock  beneficially  owned by  Elliott
International and EICA.

     (e) Not applicable.



                                   SIGNATURES

     After reasonable  inquiry and to the best of its knowledge and belief,  the
undersigned  each certifies that the information with respect to it set forth in
this statement is true, complete and correct.

Dated: January 20, 2005

         ELLIOTT ASSOCIATES, L.P.
         By:  Elliott Capital Advisors, L.P., as General Partner
                  By: Braxton Associates, Inc., as General Partner


                      By:/s/ Elliot Greenberg
                         -------------------- 
                             Elliot Greenberg
                             Vice President


         ELLIOTT INTERNATIONAL, L.P.
         By:  Elliott International Capital Advisors Inc.,
                 as Attorney-in-Fact


                      By:/s/ Elliot Greenberg
                         -------------------- 
                             Elliot Greenberg
                             Vice President


         ELLIOTT INTERNATIONAL CAPITAL ADVISORS INC.


         By:/s/ Elliot Greenberg
            -------------------- 
                Elliot Greenberg
                Vice President